BNUM2248
NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis)(CPTC-NME2-2), 1mg/mL
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- BNUM2248
- Zusätzliche Namen:
- C myc purine binding transcription factor PUF; C-myc purine-binding transcription factor PUF; epididymis secretory sperm binding protein Li 155an; HEL-S-155an; Histidine protein kinase NDKB; ; NDP kinase B; NDPKB; nm23-H2; NM23B; NME/NM23 nucleoside diphosphate kinase 2; nme2; Nucleoside diphosphate kinase B
- Anwendung:
- WB, IHC-P
- Konzentration:
- 1 mg/ml
- Molekulargewicht:
- 17 kDa
- Quelle:
- Animal
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Biotium
- Host:
- Mouse
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, no BSA, no azide|PBS, no BSA, no sodium azide
- Immunogen:
- Recombinant full-length human NME2 protein
- Formulierung:
- PBS, no BSA, no azide
- Klon:
- CPTC-NME2-2
- Uniprot:
- P22392
- Synonyme:
- c-myc purine-binding transcription factor PUF;c-myc transcription factor;epididymis secretory sperm binding protein Li 155an;HEL-S-155an;histidine protein kinase NDKB;NDKB;NDP kinase B;NDPK-B;NDPKB;NM23-H2;NM23-LV;NM23B;NME1-NME2 protein;NME1-NME2 readthrough transcript;NMELV;non-metastatic cells 2, protein (NM23) expressed in;non-metastatic cells 2, protein (NM23B) expressed in;nucleoside diphosphate kinase B;nucleotide diphosphate kinase B;PUF
- Weitere Details:
- The nm23 gene, a potential suppressor of metastasis, was originally identified by differential hybridization between two murine melanoma sub-lines, one with a high and the second with a low metastatic capacity. Highly metastatic sub-lines exhibit much lower levels of nm23 than less metastatic cells. Based on sequence analysis, nm23 appears highly related to nucleotide diphosphate kinases (NDP). In humans, NDP kinases A and B are identical to two isotypes of human nm23 homologs, namely nm23-H1 and H2, respectively. nm23-H2 is identical in sequence to PuF, a transcription factor that binds to nuclease hypersensitive elements at positions 142 to 115 of the human c-Myc promotor. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Versandbedingungen:
- Ambient