Ezrin / p81(CPTC-Ezrin-1), 1mg/mL

Eine Lieferung in diese Region ist nicht möglich.

SKU:: BNUM2238
Zusätzliche Namen:: Villin-2; CVIL; Epididymis secretory protein Li 105; EZR; p81; VIL2; Cytovillin; Cytovillin 2; HEL S 105; DKFZp762H157
Anwendung:: WB, IHC-P
Konzentration:: 1 mg/ml
Molekulargewicht:: 87 kDa
Quelle:: Animal
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Biotium
Host:: Mouse
Reaktivitäten:: Human, Mouse
Buffer:: PBS, no BSA, no azide|PBS, no BSA, no sodium azide
Immunogen:: Recombinant human full-length Ezrin protein
Formulierung:: PBS, no BSA, no azide
Klon:: CPTC-Ezrin-1
Uniprot:: P15311
Synonyme:: CVIL;CVL;Cytovillin;cytovillin 2;epididymis secretory protein Li 105;ezrin;HEL-S-105;p81;VIL2;villin 2 (ezrin);Villin-2
Weitere Details:: Ezrin, Moesin and Radixin belong to a family of highly homologous actin-associated proteins that are localized just beneath the plasma membrane. The proteins are believed to be involved in the mediation of interactions between cytoskeletal and membrane proteins. Ezrin serves as a major cytoplasmic substrate of various protein-tyrosine kinases, including the epidermal growth factor receptor. Ezrin has also been identified as a cAMP-dependent protein kinase (A-kinase) anchoring protein and designated AKAP78. Moesin and Radixin share over 70% homology with Ezrin and are co-expressed within various cell types. Despite the high degree of homology, the three proteins exhibit a distinct receptor-specific pattern of phosphorylation. Overexpression of Ezrin predicts the poor prognosis of gastric adenocarcinoma. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Versandbedingungen:: Ambient