BNUM2146
PU.1 (SPI-1) (B-Cell Marker) (PU1/2146), 1mg/mL
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- BNUM2146
- Zusätzliche Namen:
- Transcription Factor spi1; 31kDa Transforming Protein; Hematopoietic Transcription Factor PU.1; SFPI1; SPI1; SPIA; Spleen focus forming virus (SFFV) proviral integration oncogene spi1
- Anwendung:
- Flow Cytometry, WB, IHC-P, IF
- Konzentration:
- 1 mg/ml
- Molekulargewicht:
- 40 kDa
- Quelle:
- Animal
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Biotium
- Host:
- Mouse
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, no BSA, no azide|PBS, no BSA, no sodium azide
- Immunogen:
- Recombinant fragment (around aa 16-170) of human PU.1 protein (Exact sequence is proprietary)
- Formulierung:
- PBS, no BSA, no azide
- Klon:
- PU1/2146
- Uniprot:
- P17947
- Synonyme:
- 31 kDa transforming protein;31 kDa-transforming protein;hematopoietic transcription factor PU.1;OF;PU.1;SFPI1;SPI-1;SPI-A;spleen focus forming virus (SFFV) proviral integration oncogene spi1;transcription factor PU.1
- Weitere Details:
- PU.1 is a member of the ETS family of transcription factors and is important for normal B-cell development. It is expressed in the myeloid lineage and in immature as well as mature B-lymphocytes, with the exception of plasma cells. PU.1 is expressed in germinal center B-cells and mantle B-cells. Various lymphomas are also positive for this marker. It is essential during early B-cell differentiation. The absence of PU.1 results in total block of B-cell development at the pre-pro stage. PU.1 plays a key role in normal myeloid differentiation, and regulates the expression of immunoglobulin and other genes that are important for B-cell development. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Versandbedingungen:
- Ambient