BNUM2097
Human IgD (Immunoglobulin Delta Heavy Chain) (B-Cell Marker)(IgD26), 1mg/mL
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- BNUM2097
- Zusätzliche Namen:
- Ig delta chain C region; IGHD; Immunoglobulin heavy constant delta
- Anwendung:
- IHC-P
- Konzentration:
- 1 mg/ml
- Molekulargewicht:
- 44-80 kDa (heavy chain); 21-25 kDa (kappa light chain)
- Quelle:
- Animal
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Biotium
- Host:
- Mouse
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, no BSA, no azide|PBS, no BSA, no sodium azide
- Immunogen:
- Full-length human IGHD protein
- Formulierung:
- PBS, no BSA, no azide
- Klon:
- IgD26
- Uniprot:
- P01880
- Synonyme:
- constant region of heavy chain of IgD;HIATL1;hippocampus abundant transcript-like 1;hippocampus abundant transcript-like protein 1;Ig delta chain C region;Ig delta chain C region NIG-65;Ig delta chain C region WAH
- Weitere Details:
- Immunoglobulins are four-chain, Y-shaped, monomeric structures comprised of two identical heavy chains and two identical light chains held together through interchain disulfide bonds. The chains form two domains, the Fab (antigen binding) fragment and the Fc (constant) fragment. Immunoglobulin D (IgD) exists as a monomer with light chains. It plays a biological role as a transmembrane receptor molecule, co-expressed with IgM on the surface of mature/naive B cells. In particular, it is found on spleen B cell surfaces. Compared to IgM, IgD exists in much lower numbers and is not expressed on immature B cells. IgD surface expression on B cells is regulated in part by IL-27. In mice, the inhibition of this immunoglobulin isotype does not cause a significant change to the immune system. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Versandbedingungen:
- Ambient