BNUM1867
CD8A (Cytotoxic-&Suppressor T-Cell Marker) (rC8/468), 0.2mg/mL
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- BNUM1867
- Zusätzliche Namen:
- CD8 antigen; alpha polypeptide (p32); T8/Leu-2 T-lymphocyte differentiation antigen; Ly3; LYT3; MAL; T-cell surface glycoprotein CD8 alpha chain
- Anwendung:
- IHC-P
- Konzentration:
- 1 mg/ml
- Molekulargewicht:
- 32 kDa
- Quelle:
- Animal
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Biotium
- Host:
- Mouse
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, no BSA, no azide|PBS, no BSA, no sodium azide
- Immunogen:
- Recombinant full-length human CD8a protein
- Formulierung:
- PBS, no BSA, no azide
- Klon:
- rC8/468
- Uniprot:
- P01732
- Synonyme:
- CD8;CD8 antigen, alpha polypeptide (p32);Cgn2;CNCalpha4, CNG5;CNG channel alpha-4;CNG-4;CNG4;cyclic nucleotide gated cation channel;cyclic nucleotide gated channel alpha 4;cyclic nucleotide-gated cation channel alpha-4;cyclic nucleotide-gated olfactory channel subunit OCNC2;Leu2;Leu2 T-lymphocyte antigen;OKT8 T-cell antigen;olfactory cyclic nucleotide-gated channel;p32;rOCNC2;T cell co-receptor;T-cell antigen Leu2;T-cell surface glycoprotein CD8 alpha chain;T-lymphocyte differentiation antigen T8/Leu-2;T8 T-cell antigen
- Weitere Details:
- CD8 is a cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha/beta) or as a homodimer (CD8 alpha/alpha). A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class 1 and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells. For mature T-cells, CD4 and CD8 are mutually exclusive, so anti-CD8, generally used in conjunction with anti-CD4.It is a useful marker for distinguishing helper/inducer T-lymphocytes, and most peripheral T-cell lymphomas are CD4 /CD8-. Anaplastic large cell lymphoma is usually CD4 and CD8-, and in T-lymphoblastic lymphoma/leukemia, CD4 and CD8 are often co-expressed. CD8 is also found in littoral cell angioma of the spleen.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Versandbedingungen:
- Ambient