BNUM1832
Spectrin Alpha 1 (Erythrocyte Marker)(SPTA1/1832), 1mg/mL
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- BNUM1832
- Zusätzliche Namen:
- Alpha I spectrin; Elliptocytosis 2 (EL2); Erythrocyte alpha spectrin; Erythroid alpha-spectrin; HPP; HS3; Spectrin alpha erythrocytic 1; SPH3; SPTA1
- Anwendung:
- WB, IHC-P
- Konzentration:
- 1 mg/ml
- Molekulargewicht:
- 240 kDa
- Quelle:
- Animal
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Biotium
- Host:
- Mouse
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, no BSA, no azide|PBS, no BSA, no sodium azide
- Immunogen:
- Recombinant human SPTA fragment (around aa356-475) (exact sequence is proprietary)
- Formulierung:
- PBS, no BSA, no azide
- Klon:
- SPTA1/1832
- Uniprot:
- P02549
- Synonyme:
- alpha-I spectrin;EL2;elliptocytosis 2;erythroid alpha-spectrin;HPP;HS3;spectrin alpha chain, erythrocyte;spectrin alpha chain, erythrocytic 1;SPH3;SPTA
- Weitere Details:
- Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. Spectrins function as membrane organizers and stabilizers, composed of non-homologous A Alpha andB Beta chains, which aggregate side-to-side in an anti-parallel fashion to form dimers, tetramers and higher polymers. Spectrin A Alpha I and spectrinB Beta I are present in erythrocytes, whereas spectrin A Alpha II (also designated fodrin A Alpha) and spectrinB Beta II (also designated fodrinB Beta) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Versandbedingungen:
- Ambient