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BNUM1575

Tyrosinase-Related Protein-1 (TYRP-1) (Melanoma Marker), 1mg/mL

Eine Lieferung in diese Region ist nicht möglich.

SKU:
BNUM1575
Zusätzliche Namen:
5; 6 dihydroxyindole 2 carboxylic acid oxidase; 6-dihydroxyindole-2-carboxylic acid oxidase; Associated with iris pigmentation; CAS2; Catalase B (CATB); DHICA oxidase; Glycoprotein75 (GP75); Melanoma antigen gp75; Tyrosinase-related protein 1 (TYRP1); TYRRP
Anwendung:
IHC-P
Konzentration:
1 mg/ml
Molekulargewicht:
75 kDa
Quelle:
Animal
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Biotium
Host:
Rabbit
Reaktivitäten:
Human, Mouse, Rabbit
Buffer:
PBS, no BSA, no azide|PBS, no BSA, no sodium azide
Immunogen:
Recombinant human TYRP1 protein
Formulierung:
PBS, no BSA, no azide
Uniprot:
P17643
Synonyme:
5,6-dihydroxyindole-2-carboxylic acid oxidase;b-PROTEIN;CAS2;catalase B;CATB;DHICA oxidase;glycoprotein 75;GP75;melanoma antigen gp75;OCA3;TRP;TRP1;Tyrosinase-related protein 1;TYRP
Weitere Details:
Reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Versandbedingungen:
Ambient