BNUM1547
CD137L / 4-1BBL / TNFSF9(CD137L/1547), 1mg/mL
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- BNUM1547
- Zusätzliche Namen:
- 4-1BB ligand; 4-1BBL; CD137L; ILA ligand (TNF related); Ly63l; Tumor necrosis factor ligand 5A (TNLG5A); Tumor necrosis factor ligand superfamily member 9 (TNFSF9)
- Anwendung:
- Flow Cytometry, IHC-P
- Konzentration:
- 1 mg/ml
- Molekulargewicht:
- 27 kDa
- Quelle:
- Animal
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Biotium
- Host:
- Mouse
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, no BSA, no azide|PBS, no BSA, no sodium azide
- Immunogen:
- Recombinant full-length human CD137L protein
- Formulierung:
- PBS, no BSA, no azide
- Klon:
- CD137L/1547
- Uniprot:
- P41273
- Synonyme:
- 4-1BB ligand;4-1BB-L;4-1BBL;beta chemokine receptor-like 1;C-X3-C CKR-1;CCRL1;CD137 ligand;CD137L;chemokine (C-C) receptor-like 1;chemokine (C-X3-C motif) receptor 1;chemokine (C-X3-C) receptor 1;CMK-BRL-1;CMK-BRL1;CMKBRL1;CMKDR1;CX3C chemokine receptor 1;fractalkine receptor;G-protein coupled receptor 13;GPR13;GPRV28;homolog of mouse 4-1BB-L;receptor 4-1BB ligand;TNLG5A;tumor necrosis factor (ligand) superfamily, member 9;tumor necrosis factor ligand 5A;tumor necrosis factor ligand superfamily member 9;tumor necrosis factor superfamily member 9;V28
- Weitere Details:
- TNFSF9 / 4-1BBL is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9 / 4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9 / 4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. It has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine is required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Versandbedingungen:
- Ambient