BNUM1435
Desmoglein-1 (DSG1) (18D4), 1mg/mL
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- BNUM1435
- Zusätzliche Namen:
- Cadherin family member 4; CDHF4; Desmoglein-1; Desmosomal glycoprotein 1; DG1; DSG1; EPKHE; EPKHIA; Pemphigus foliaceus antigen; PPKS1; SPPK1
- Anwendung:
- WB, IHC-P, IF
- Konzentration:
- 1 mg/ml
- Molekulargewicht:
- 150 kDa (precursor); 160 kDa (mature)
- Quelle:
- Animal
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Biotium
- Host:
- Mouse
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, no BSA, no azide|PBS, no BSA, no sodium azide
- Immunogen:
- Human desmoglein-1 intracellular domain (exact sequence is proprietary)
- Formulierung:
- PBS, no BSA, no azide
- Klon:
- 18D4
- Uniprot:
- Q02413
- Synonyme:
- cadherin family member 4;CDHF4;desmoglein-1;desmosomal glycoprotein 1;DG1;DSG;EPKHE;EPKHIA;GBP-1;GTP-binding protein 1;guanine nucleotide-binding protein 1;guanylate binding protein 1, interferon-inducible, 67kDa;guanylate-binding protein 1;huGBP-1;interferon-induced guanylate-binding protein 1;pemphigus foliaceus antigen;PPKS1;SPPK1
- Weitere Details:
- This antibody recognizes a protein of ~150 kDa, identified as Desmoglein-1 (DSG1). Desmoglein-1 is a member of the desmosomal cadherin family. Desmosomes are intercellular adhering junctions that represent cell surface attachment sites for intermediate filament. Desmocollins and desmogleins are the main desmosomal transmembrane proteins. Desmogleins consist of Dsg1, Dsg2, Dsg3, and Dsg4 isoforms. Within the desmosome, the extracellular domain of desmoglein is essential for calcium dependent heterophilic binding to the desmocollins, whereas the intracellular domain is essential for binding to the desmosomal plaque protein, plakoglobin. Desmoglein 1 is synthesized exclusively in the suprabasal layers. Intact and functionally active desmoglein 1 is essential to epidermal integrity.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Versandbedingungen:
- Ambient