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BNUM1154

Mucin 3(MUC3/1154), 1mg/mL

Eine Lieferung in diese Region ist nicht möglich.

SKU:
BNUM1154
Zusätzliche Namen:
Intestinal mucin-3A; intestinal mucin-like; MUC3; MUC3A; MUC3B; mucin 3, intestinal; mucin 3A, cell surface associated; mucin 3A, intestinal; mucin 3B, cell surface associated
Anwendung:
IHC-P
Konzentration:
1 mg/ml
Molekulargewicht:
1100 kDa
Quelle:
Animal
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Biotium
Host:
Mouse
Reaktivitäten:
Human, Mouse
Buffer:
PBS, no BSA, no azide|PBS, no BSA, no sodium azide
Immunogen:
A synthetic peptide of 35 amino acids, SIB35 (C-HSTPSFTSSITTTETTSHSTPSFTSSITTTETTS), which contains two of the MUC3 tandem repeats, coupled to KLH.
Formulierung:
PBS, no BSA, no azide
Klon:
MUC3/1154
Uniprot:
Q02505, Q9H195
Synonyme:
intestinal mucin;intestinal mucin MUC3B;Intestinal mucin-3A;intestinal mucin-3B;MUC-3A;MUC-3B;MUC3;MUC3A;mucin 3, intestinal;mucin-3A;mucin-3B
Weitere Details:
This antibody recognizes a protein of HMW, identified as mucin 3 glycoprotein (MUC3). This MAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC2. The Mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs) encoded by 60 base pairs (Mucin 1), 69 base pairs (Mucin 2) and 51 base pairs (Mucin 3). The number of repeats is highly polymorphic and varies among different alleles. Mucin 1 proteins are expressed as type I membrane proteins in addition to secreted forms. Mucin 1 is aberrantly expressed in epithelial tumors including breast carcinomas. Mucin 2 coats the epithelia of the intestines and airways and is associated with colonic tumors. Mucin 3 is a major component of various mucus gels and is broadly expressed in normal and tumor cells.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Versandbedingungen:
Ambient