BNUM1096
MHC II (HLA-DRA)(169-1B5.2), 1mg/mL
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- BNUM1096
- Zusätzliche Namen:
- Ia3; Ia-3; H-2Ea; H2-Ea; AI323765; I-Ealpha; E-alpha-f; MHC-H2-Ea
- Anwendung:
- Flow Cytometry, IF
- Konzentration:
- 1 mg/ml
- Molekulargewicht:
- 36 kDa (? chain) and 27 kDa (? chain)
- Quelle:
- Animal
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Biotium
- Host:
- Mouse
- Reaktivitäten:
- Bovine, Human, Mouse, Feline
- Buffer:
- PBS, no BSA, no azide|PBS, no BSA, no sodium azide
- Immunogen:
- Human peripheral blood leukocytes
- Formulierung:
- PBS, no BSA, no azide
- Klon:
- 169-1B5.2
- Uniprot:
- P01903
- Synonyme:
- histocompatibility antigen HLA-DR alpha;HLA class II histocompatibility antigen, DR alpha chain;HLA-DRA1;MHC class II antigen DRA
- Weitere Details:
- This antibody detects a monomorphic general framework determinant of HLA-DR Class II antigen. It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kDa alpha (heavy) chain and a 28 kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4 T cells. It is an excellent histiocytic marker in paraffin sections producing intense cytoplasmic staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Versandbedingungen:
- Ambient