Ksp-Cadherin / CDH16(CDH16/1071), 1mg/mL

Eine Lieferung in diese Region ist nicht möglich.

SKU:: BNUM1071
Zusätzliche Namen:: Cadherin-16 (CDH16); Kidney-specific cadherin; Ksp-cadherin antibody
Anwendung:: WB, IHC-P, IF
Konzentration:: 1 mg/ml
Molekulargewicht:: 130 kDa
Quelle:: Animal
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Biotium
Host:: Mouse
Reaktivitäten:: Canine, Human, Mouse, Rabbit
Buffer:: PBS, no BSA, no azide|PBS, no BSA, no sodium azide
Immunogen:: Recombinant human CDH16 protein
Formulierung:: PBS, no BSA, no azide
Klon:: CDH16/1071
Uniprot:: O75309
Synonyme:: cadherin 16, KSP-cadherin;cadherin-16;kidney-specific cadherin;KSP-cadherin
Weitere Details:: This MAb recognizes a protein of 130 kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels. Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Versandbedingungen:: Ambient