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BNUM0917

Mucin 5AC (MUC5AC)(MUC5AC/917), 1mg/mL

Eine Lieferung in diese Region ist nicht möglich.

SKU:
BNUM0917
Zusätzliche Namen:
Apomucin Major Airway Glycoprotein, Mucin 5 subtype AC tracheobronchial, Mucin 5 Subtypes A And C, Mucin 5AC oligomeric mucus/gel forming, Tracheobronchial Mucin (TBM)
Anwendung:
IHC-P
Konzentration:
1 mg/ml
Molekulargewicht:
641 kDa
Quelle:
Animal
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Biotium
Host:
Mouse
Reaktivitäten:
Human, Mouse
Buffer:
PBS, no BSA, no azide|PBS, no BSA, no sodium azide
Immunogen:
Recombinant human MUC5AC protein
Formulierung:
PBS, no BSA, no azide
Klon:
MUC5AC/917
Uniprot:
P98088
Synonyme:
gastric mucin;leB;lewis B blood group antigen;major airway glycoprotein;MUC5;mucin;mucin 5, subtypes A and C, tracheobronchial/gastric;mucin 5AC, oligomeric mucus/gel-forming pseudogene;mucin-5 subtype AC, tracheobronchial;mucin-5AC;TBM;tracheobronchial mucin
Weitere Details:
Mucin 5AC glycoprotein (MUC5AC) is a 641 kDa glycoprotein belonging to the superfamily of mucins. Mucins are high molecular weight glycoproteins produced by epithelial cells and can be divided into two families; secretory mucins and membrane bound mucins. MUC5AC is a mucus-forming secreted mucin that is found in normal gastric and tracheo-bronchial mucosa, but absent from normal colon. MUC5AC expression is present in primary ovarian mucinous cancer but usually absent in colorectal adenocarcinoma, thus showing an expression pattern opposite to MUC2. Together with a panel of antibodies, Anti-MUC5AC may be useful for differential identification of primary mucinous ovarian tumors from colon adenocarcinoma metastatic to the ovary. MUC5AC antibodies may also be useful for identification of intestinal metaplasia as well as in the identification of pancreatic carcinoma and pre-cancerous changes vs. normal pancreas. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Versandbedingungen:
Ambient