BNUM0909
c-Myc(MYC909), 1mg/mL
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- BNUM0909
- Zusätzliche Namen:
- Class E basic helix-loop-helix protein 39 (bHLHe39); MRTL; Myc2; Niard; Nird; Proto-oncogene c-Myc; RNCMYC; Transcription factor p64; Transcriptional regulator Myc-A; V-Myc avian myelocytomatosis viral oncogene homolog
- Anwendung:
- IHC-P
- Konzentration:
- 1 mg/ml
- Molekulargewicht:
- 62-64 kDa
- Quelle:
- Animal
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Biotium
- Host:
- Mouse
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, no BSA, no azide|PBS, no BSA, no sodium azide
- Immunogen:
- Recombinant human c-myc protein
- Formulierung:
- PBS, no BSA, no azide
- Klon:
- MYC909
- Uniprot:
- P01106
- Synonyme:
- avian myelocytomatosis viral oncogene homolog;bHLHe39;c-Myc;class E basic helix-loop-helix protein 39;MRTL;myc proto-oncogene protein;myc-related translation/localization regulatory factor;MYCC;proto-oncogene c-Myc;transcription factor p64;v-myc avian myelocytomatosis viral oncogene homolog;v-myc myelocytomatosis viral oncogene homolog
- Weitere Details:
- This antibody recognizes a transcription factor of 64-67 kDa, identified as c-myc. This MAb shows no cross-reaction with v-myc. c-myc is involved in the control of cell proliferation and differentiation and is amplified and/or over-expressed in a variety of tumors. Over-expression of c-myc protein occurs frequently in luminal cells of prostate intraepithelial neoplasia as well as in most primary carcinomas and metastatic disease. Rearrangement of the MYC gene is found in 3% to 16% of diffuse large B-cell lymphoma (DLBCL's) and in nearly 100% of Burkitt lymphomas (BL). Identifying MYC status is important in establishing final diagnosis of DLBCL, BL, or B-cell lymphoma, with features intermediate between DLBCL and BL as well as in differential diagnoses of the lymphomas.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Versandbedingungen:
- Ambient