BNUM0761
Human IgA Immunoglobulin(IA761), 1mg/mL
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- BNUM0761
- Zusätzliche Namen:
- A2m Marker; Ig alpha 1 Chain C Region; Ig alpha 2 Chain C Region; IGHA1; IGHA2; Immunoglobulin Am1; Immunoglobulin Am2; Immunoglobulin Heavy Constant Alpha 1; Immunoglobulin Heavy Constant Alpha 2
- Konzentration:
- 1 mg/ml
- Molekulargewicht:
- 50-75 kDa
- Quelle:
- Animal
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Biotium
- Host:
- Mouse
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, no BSA, no azide|PBS, no BSA, no sodium azide
- Immunogen:
- Purified human alpha heavy chain
- Formulierung:
- PBS, no BSA, no azide
- Klon:
- IA761
- Uniprot:
- P01876, P01877
- Synonyme:
- A2M;constant region of heavy chain of IgA2;Ig alpha-1 chain C region;Ig alpha-1 chain C region BUR;Ig alpha-1 chain C region TRO;Ig alpha-2 chain C region;Ig alpha-2 chain C region BUT;Ig alpha-2 chain C region LAN;IgA1;immunoglobulin alpha 1;immunoglobulin alpha 2 (A2M marker);immunoglobulin heavy chain constant region alpha 1
- Weitere Details:
- This MAb is specific to heavy chain of IgA and shows minimal cross-reaction with heavy chains of other immunoglobulins. It is reactive with all subclasses of Alpha heavy chain. Immunoglobulins are four-chain, Y-shaped, monomeric structures comprised of two identical heavy chains and two identical light chains held together through inter-chain disulfide bonds. The chains form two domains, the Fab (antigen binding) fragment and the Fc (constant) fragment. Immunoglobulin A (IgA) is the main protein of the mucosal immune system. It is generated by B-cells in gut-associated lymphoid tissues. Daily production of IgA exceeds that of any of the other immunoglobulins.IgA exists mainly in dimers but can also exist as polymers or as monomers. Dimers and polymers contain a joining (J) chain that can be bound by the polymeric immunoglobulin receptor (pIgR) for transportation of the molecule to mucosal surfaces. The most common feature of plasmacytomas, and certain non-Hodgkin's lymphomas is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Versandbedingungen:
- Ambient