BNUM0729
Ku-Holo (p70;83)(KU729), 1mg/mL
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- BNUM0729
- Zusätzliche Namen:
- Ku (p70): 70kDa subunit of Ku antigen; ATP dependent DNA helicase 2 subunit 1; ATP-dependent DNA helicase II 70kDa subunit; CTC box-binding factor 75kDa subunit; CTC75; CTCBF; DNA repair protein XRCC6; G22P1; Ku autoantigen, 70kDa; Ku70; Kup70; Lupus Ku autoantigen protein p70; ML8; Thyroid autoantigen 70kD (Ku antigen); Thyroid-lupus autoantigen (TLAA); X-ray repair cross-complementing protein 6 (XRCC6) Ku (p80): 86kDa subunit of Ku antigen; ATP dependent DNA helicase 2 subunit 2; ATP dependent DNA helicase II 86Kd subunit; ATP-dependent DNA helicase II 80kDa subunit; CTC box-binding factor 85kDa subunit; CTC85; CTCBF; DNA repair protein XRCC5; KARP1; Ku autoantigen 80kDa; Ku80; Ku86 autoantigen related protein 1; KUB2; Lupus Ku autoantigen protein p86; Nuclear factor IV (NFIV); Thyroid-lupus autoantigen (TLAA); X-ray repair cross-complementing protein 5 (XRCC5)
- Anwendung:
- Flow Cytometry, IF
- Konzentration:
- 1 mg/ml
- Molekulargewicht:
- 70 kDa & 80 kDa
- Quelle:
- Animal
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Biotium
- Host:
- Mouse
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, no BSA, no azide|PBS, no BSA, no sodium azide
- Immunogen:
- Nuclear extract of human HL-60 cells
- Formulierung:
- PBS, no BSA, no azide
- Klon:
- KU729
- Uniprot:
- P12956, P13010
- Synonyme:
- 5'-deoxyribose-5-phosphate lyase Ku70;5'-dRP lyase Ku70;70 kDa subunit of Ku antigen;86 kDa subunit of Ku antigen;ATP-dependent DNA helicase 2 subunit 1;ATP-dependent DNA helicase 2 subunit 2;ATP-dependent DNA helicase II 70 kDa subunit;ATP-dependent DNA helicase II 80 kDa subunit;ATP-dependent DNA helicase II, 70 kDa subunit;CTC box binding factor 75 kDa subunit;CTC box-binding factor 75 kDa subunit;CTC box-binding factor 85 kDa subunit;CTC75;CTC85;CTCBF;DNA repair protein XRCC5;DNA repair protein XRCC6;G22P1;KARP-1;KARP1;Ku autoantigen p70 subunit;Ku autoantigen, 70kDa;Ku autoantigen, 80kDa;KU70;KU80;Ku86;Ku86 autoantigen related protein 1;KUB2;lupus Ku autoantigen protein p70;lupus Ku autoantigen protein p86;ML8;NFIV;nuclear factor IV;thyroid autoantigen 70kD (Ku antigen);thyroid autoantigen 70kDa (Ku antigen);thyroid-lupus autoantigen;thyroid-lupus autoantigen p70;TLAA;X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining);X-ray repair complementing defective repair in Chinese hamster cells 6;X-ray repair cross-complementing protein 5;X-ray repair cross-complementing protein 6
- Weitere Details:
- Recognizes a dimer of two proteins of 70 kDa and ~80 kDa, identified as two subunits of Ku. This MAb recognizes a conformational epitope of p70/p80 dimer, which is destroyed during Western blotting. The p70/p80 dimer is important for function of a 460 kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Versandbedingungen:
- Ambient