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BNUM0702

Melanoma Marker(HMB45 + A103 + T311), 1mg/mL

Eine Lieferung in diese Region ist nicht möglich.

SKU:
BNUM0702
Zusätzliche Namen:
Melanoma antigen recognized by T-cells 1 (MART-1), MLAN-A; TYR; PMEL17
Anwendung:
WB, IHC-P
Konzentration:
1 mg/ml
Molekulargewicht:
20-22 kDa (doublet) (MART); 70-80 kDa (Tyrosinase); 90-100 kDa (gp100)
Quelle:
Animal
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Biotium
Host:
Mouse
Reaktivitäten:
Human, Mouse
Buffer:
PBS, no BSA, no azide|PBS, no BSA, no sodium azide
Immunogen:
Recombinant hMART-1 protein (A103); Recombinant tyrosinase protein (T311); Extract of pigmented melanoma metastases from lymph nodes (HMB45)
Formulierung:
PBS, no BSA, no azide
Klon:
HMB45 A103 T311
Synonyme:
antigen LB39-AA;antigen SK29-AA;ATN;CMM8;D12S53E;epididymis secretory sperm binding protein;gp100;LB24-AB;MART-1;MART1;ME20;ME20-M;ME20M;melanocyte protein mel 17;melanocyte protein PMEL;melanocyte protein Pmel 17;melanocytes lineage-specific antigen GP100;melanoma antigen recognized by T-cells 1;melanoma-associated ME20 antigen;melanosomal matrix protein17;monophenol monooxygenase;OCA1;OCA1A;OCAIA;oculocutaneous albinism IA;P1;P100;PMEL17;protein Melan-A;SHEP3;SI;SIL;SILV;silver locus protein homolog;silver, mouse, homolog of;SK29-AB;tumor rejection antigen AB;tyrosinase
Weitere Details:
This antibody cocktail recognizes three melanoma-specific proteins, which include MART-1, Tyrosinase and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. The function of gp100 is not known but it is reported to be a useful marker for melanocytes and melanomas. This cocktail of three markers is designed for extremely sensitive labeling of formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Versandbedingungen:
Ambient