BNUM0675
Cytokeratin 6(LHK6), 1mg/mL
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- BNUM0675
- Zusätzliche Namen:
- CK6A, CK6B, CK6C, CK6D, CK6E, Keratin Type II Cytoskeletal 6A, Keratin Type II Cytoskeletal 6B, Keratin Type II Cytoskeletal 6C, Keratin Type II Cytoskeletal 6D, Keratin Type II Cytoskeletal 6E, KRT6, KRT6A, KRT6B, KRT6C, KRT6D, KRT6E
- Anwendung:
- IHC-P
- Konzentration:
- 1 mg/ml
- Molekulargewicht:
- 56 kDa
- Quelle:
- Animal
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Biotium
- Host:
- Mouse
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, no BSA, no azide|PBS, no BSA, no sodium azide
- Immunogen:
- A synthetic peptide of 11 amino acids (GSSTIKYTTTS) from C-terminus of human keratin 6
- Formulierung:
- PBS, no BSA, no azide
- Klon:
- LHK6
- Synonyme:
- CK-6B;CK-6C;CK-6E;CK6A;CK6B;CK6C;CK6D;cytokeratin 6A;cytokeratin 6B;cytokeratin 6C;cytokeratin 6D;cytokeratin-6C;cytokeratin-6E;K6A;K6B;K6C;K6D;K6E;keratin 6A, , type II;keratin 6A, type II;keratin 6B, type II;keratin 6C, type II;keratin 6E;keratin K6h;keratin-like 1 (a type II keratin sequence);keratin, epidermal type II, K6A;keratin, epidermal, type II, K6B;keratin, type II cytoskeletal 6A;keratin, type II cytoskeletal 6B;keratin, type II cytoskeletal 6C;KRT6C;KRT6D;KRT6E;KRTL1;PC2;PC3;PC4;PPKNEFD;type-II keratin Kb10;type-II keratin Kb12;type-II keratin Kb6
- Weitere Details:
- This MAb recognizes a protein of 56 kDa, identified as cytokeratin 6 (CK6). In humans, multiple isoforms of Cytokeratin 6 (6A-6F), encoded by several highly homologous genes, have distinct tissue expression patterns, and Cytokeratin 6A is the dominant form in epithelial tissue. The gene encoding human Cytokeratin 6A maps to chromosome 12q13, and mutations in this gene are linked to several inheritable hair and skin pathologies. Keratins 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyper-proliferation-related keratins). Keratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyper-proliferative situations. Epidermal injury results in activation of keratinocytes, which express CK6 and CK16. CK6 is strongly expressed in about 75% of head and neck squamous cell carcinomas. Expression of CK6 is particularly associated with differentiation. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Versandbedingungen:
- Ambient