CD146 / MCAM / MUC18 / Mucin 18(C146/634), 1mg/mL

Eine Lieferung in diese Region ist nicht möglich.

SKU:: BNUM0634
Zusätzliche Namen:: Cell Surface Glycoprotein MUC18; Cell Surface Glycoprotein P1H12; Gicerin; Melanoma Adhesion Molecule (MCAM); Melanoma Associated Glycoprotein MUC18; Melanoma Cell Adhesion Molecule; Melanoma-associated Antigen A32; Mel-CAM; S-endo 1 Endothelial-associated Antigen; Sendo1
Anwendung:: IHC-P
Konzentration:: 1 mg/ml
Molekulargewicht:: 130 kDa
Quelle:: Animal
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Biotium
Host:: Mouse
Reaktivitäten:: Human, Mouse
Buffer:: PBS, no BSA, no azide|PBS, no BSA, no sodium azide
Immunogen:: Recombinant human CD146 protein
Formulierung:: PBS, no BSA, no azide
Klon:: C146/634
Uniprot:: P43121
Synonyme:: CD146;cell surface glycoprotein MUC18;cell surface glycoprotein P1H12;Gicerin;HEMCAM;melanoma adhesion molecule;Melanoma cell adhesion molecule;melanoma-associated antigen A32;melanoma-associated antigen MUC18;MelCAM;METCAM;MUC18;S-endo 1 endothelial-associated antigen
Weitere Details:: The human CD146 gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18, that belongs to the immunoglobulin superfamily and functions as a Ca2 -independent cell adhesion molecule. CD146 expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. CD146 is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Versandbedingungen:: Ambient