BNUM0257
Cytokeratin, HMW(AE-3), 1mg/mL
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- BNUM0257
- Zusätzliche Namen:
- KRT2B; KRT2P; HUMCYT2A; Keratin, type II Cytoskeletal 2 oral; K76; Keratin 2p (K2P); Keratin-76; Cytokeratin-2P (CK-2P; Type-II Keratin Kb9
- Anwendung:
- Flow Cytometry, WB, IHC-P, IHC-Fr, IF
- Konzentration:
- 1 mg/ml
- Molekulargewicht:
- 52-67 kDa
- Quelle:
- Animal
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Biotium
- Host:
- Mouse
- Reaktivitäten:
- Bovine, Canine, Human, Mouse, Rabbit, Rat
- Buffer:
- PBS, no BSA, no azide|PBS, no BSA, no sodium azide
- Immunogen:
- Human epidermal keratin
- Formulierung:
- PBS, no BSA, no azide
- Klon:
- AE-3
- Uniprot:
- Q01546
- Synonyme:
- CK-2P;cytokeratin 2;cytokeratin-2P;HUMCYT2A;K2P;K76;keratin 2p;keratin 76, type II;Keratin-76;keratin, type II cytoskeletal 2 oral;KRT2B;KRT2P;type-II keratin Kb9
- Weitere Details:
- This MAb recognizes basic (Type II or HMW) cytokeratins, which include 67 kDa (CK1); 64 kDa (CK3); 59 kDa (CK4); 58 kDa (CK5); 56 kDa (CK6); 52 kDa (CK8). Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50 , 48, 46, 45, and 40 kDa. MAb AE3 recognizes the 65-67, 64, 59, 58, 56, and 52 kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. AE1/AE3 is a broad spectrum anti pan-keratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Versandbedingungen:
- Ambient