BNUM0238
PLAP (Placental Alkaline Phosphatase)(ALPP/238), 1mg/mL
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- BNUM0238
- Zusätzliche Namen:
- Alkaline phosphatase placental type|Alkaline phosphatase Regan Isozyme|ALP|Alp1|ALPP|Germ-cell alkaline phosphatase|nagao Isozyme|PALP|Placental alkaline phosphatase 1|placental heat-stable alkaline phosphatase|PLAP-1|PLAP1
- Konzentration:
- 1 mg/ml
- Molekulargewicht:
- 70 kda
- Quelle:
- Animal
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Biotium
- Host:
- Mouse
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, no BSA, no azide|PBS, no BSA, no sodium azide
- Immunogen:
- Recombinant full-length human ALPP protein
- Formulierung:
- PBS, no BSA, no azide
- Klon:
- ALPP/238
- Uniprot:
- P05187
- Synonyme:
- alkaline phosphatase Regan isozyme;alkaline phosphatase, placental type;alkaline phosphomonoesterase;ALP;ALPI;glycerophosphatase;IAP;Intestinal alkaline phosphatase;Intestinal-type alkaline phosphatase;PALP;placental alkaline phosphatase 1;PLAP;PLAP-1
- Weitere Details:
- PLAP is a tissue specific, trophoblast-derived, 70 kDa, glycosyl-phosphatidylinositol (GPI)-anchored, dimeric, Zn2 metallo glycoprotein that catalyzes the hydrolysis of phosphomonoesters into an inorganic phosphate and an alcohol. It is present in the placenta and serum of pregnant women and in high frequency in gynecological and testicular cancers and in lower frequency in other tumors. The three tissue-specific AP's in humans, PLAP, germ cell AP (GCAP) and intestinal AP, are 90-98% homologous. Non-tissue specific AP is found in kidney, liver and bone. This MAb binds equally well to all common allelic variants (S, F, FS and I) of PLAP as to AP from normal human testis. This MAb can be used both as coating as well as tracer antibody in the same ELISA to detect PLAP in serum of S, F, FS and I phenotypes.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Versandbedingungen:
- Ambient