BNUM0031
Mucin 5AC (MUC5AC)(45M1), 1mg/mL
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- BNUM0031
- Zusätzliche Namen:
- Apomucin Major Airway Glycoprotein, Mucin 5 subtype AC tracheobronchial, Mucin 5 Subtypes A And C, Mucin 5AC oligomeric mucus/gel forming, Tracheobronchial Mucin (TBM)
- Anwendung:
- ELISA, Flow Cytometry, WB, IHC-P
- Konzentration:
- 1 mg/ml
- Molekulargewicht:
- >1,000 kDa
- Quelle:
- Animal
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Biotium
- Host:
- Mouse
- Reaktivitäten:
- Human, Mouse, Porcine, Rabbit, Rat, Feline
- Buffer:
- PBS, no BSA, no azide|PBS, no BSA, no sodium azide
- Immunogen:
- M1 mucin preparation from the fluid of an ovarian mucinous cyst belonging to an O Le(a-b) patient
- Formulierung:
- PBS, no BSA, no azide
- Klon:
- 45M1
- Uniprot:
- P98088
- Synonyme:
- gastric mucin;leB;lewis B blood group antigen;major airway glycoprotein;MUC5;mucin;mucin 5, subtypes A and C, tracheobronchial/gastric;mucin 5AC, oligomeric mucus/gel-forming pseudogene;mucin-5 subtype AC, tracheobronchial;mucin-5AC;TBM;tracheobronchial mucin
- Weitere Details:
- This MAb recognizes the peptide core of gastric mucin M1 (recently identified as Mucin 5AC). Its epitope is located in the C-terminal cysteine rich part of the peptide core of MUC5AC. The epitope is destroyed by beta-mercaptoethanol but not by periodate treatment. This mucin is present in primary ovarian mucinous cancer but usually absent in colorectal adenocarcinoma, thus showing an expression pattern opposite to MUC2. Together with a panel of antibodies, Anti-MUC5AC may be useful for differential identification of primary mucinous ovarian tumors from colon adenocarcinoma metastatic to the ovary. MUC5AC antibodies may also be useful for identification of intestinal metaplasia as well as in the identification of pancreatic carcinoma and pre-cancerous changes vs. normal pancreas. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Versandbedingungen:
- Ambient