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  2. Monoclonal

BNUB3393

Drebrin 1 (DBN1)(DBN1/3393), 0.2mg/mL

Eine Lieferung in diese Region ist nicht möglich.

SKU:
BNUB3393
Zusätzliche Namen:
Developmentally regulated brain protein; Drebrin 1; Drebrin; Drebrin E; Drebrin E2; Drebrin1; DrebrinE
Anwendung:
WB, IHC-P
Konzentration:
0.2 mg/ml
Molekulargewicht:
120 kDa
Quelle:
Animal
Lagerbedingungen:
2-8[o]C, RT
Hersteller:
Biotium
Host:
Mouse
Reaktivitäten:
Human
Buffer:
PBS, 0.05% BSA, 0.05% azide|PBS, 0.05% BSA, 0.05% sodium azide
Immunogen:
Recombinant fragment (aa 150-281) of human DBN1 protein (exact sequence is proprietary)
Formulierung:
PBS, 0.05% BSA, 0.05% azide
Klon:
DBN1/3393
Uniprot:
Q16643
Synonyme:
D0S117E;developmentally-regulated brain protein;drebrin;drebrin A;drebrin E;drebrin E2
Weitere Details:
Drebrins (developmentally regulated brain proteins) are cytoplasmic proteins that bind F-actin in the brain and are involved in cell migration, extension of neuronal processes and plasticity of dendrites. There are three isoforms: two embryonic types (E1 and E2); and an adult type (A), generated by alternative RNA splicing from a single Drebrin gene. Drebrins are expressed mainly in brain neurons but are also found in skeletal muscle, heart, placenta, pancreas and kidney. Drebrin has been designated as a marker of the dendritic spine. Decreases in Drebrin levels in the brain have been been associated with Alzheimer's disease and Down syndrome. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Versandbedingungen:
Ambient