Uroplakin 1B (Urothelial Differentiation Marker)(UPK1B/3081), 0.2mg/mL

Eine Lieferung in diese Region ist nicht möglich.

SKU:: BNUB3081
Zusätzliche Namen:: Tetraspanin-20; Tspan-20; TSPAN20; UP1b; UPIb; UPK1B; Uroplakin-1b
Anwendung:: IHC-P
Konzentration:: 0.2 mg/ml
Molekulargewicht:: ~30 kDa
Quelle:: Animal
Lagerbedingungen:: 2-8[o]C, RT
Hersteller:: Biotium
Host:: Mouse
Reaktivitäten:: Human
Buffer:: PBS, 0.05% BSA, 0.05% azide|PBS, 0.05% BSA, 0.05% sodium azide
Immunogen:: Recombinant fragment (around aa 109-229) of human Uroplakin 1B (UPK1B) protein (exact sequence is proprietary)
Formulierung:: PBS, 0.05% BSA, 0.05% azide
Klon:: UPK1B/3081
Uniprot:: O75841
Synonyme:: tetraspan;tetraspanin-20;tspan-20;TSPAN20;UP1b;UPIB;UPK1;uroplakin Ib;uroplakin-1b
Weitere Details:: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. UPK1B is expressed by terminally differentiated urothelial cells. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Versandbedingungen:: Ambient