BNUB3074
EGLN1 / PHD2(366G/76/3), 0.2mg/mL
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- BNUB3074
- Zusätzliche Namen:
- Chromosome 1 Open Reading Frame 12 (C1ORF12); DKFZp761F179; ECYT3; Egl 9 family hypoxia inducible factor 1; Egl nine homolog 1; Egln1; HIF Prolyl Hydroxylase 2 (HIF PH2); HIFPH2; HPH2; Hypoxia inducible factor prolyl hydroxylase 2; ORF13; P4H2; PhD2; PNAS 118; PNAS 137; Prolyl hydroxylase domain-containing protein 2; SM20; Zinc finger MYND domain containing protein 6 (ZMYND6)
- Konzentration:
- 0.2 mg/ml
- Molekulargewicht:
- 46 kDa
- Quelle:
- Animal
- Lagerbedingungen:
- 2-8[o]C, RT
- Hersteller:
- Biotium
- Host:
- Mouse
- Reaktivitäten:
- Human
- Buffer:
- PBS, 0.05% BSA, 0.05% azide|PBS, 0.05% BSA, 0.05% sodium azide
- Immunogen:
- Residues 1-24 of PHD2
- Formulierung:
- PBS, 0.05% BSA, 0.05% azide
- Klon:
- 366G/76/3
- Uniprot:
- Q9GZT9
- Synonyme:
- C1orf12;DIS3 mitotic control homolog-like;DIS3-like exonuclease 1;dis3l;ECYT3;egl nine homolog 1;egl nine-like protein 1;HALAH;HIF-PH2;HIF-prolyl hydroxylase 2;HIFPH2;HPH-2;HPH2;hypoxia-inducible factor prolyl hydroxylase 2;PHD2;prolyl hydroxylase domain-containing protein 2;SM-20;SM20;XELAEV_18018445mg;zinc finger MYND domain-containing protein 6;ZMYND6
- Weitere Details:
- This antibody recognises human prolyl hydroxylase 2 (PHD2), a 46 kDa enzyme expressed abundantly in all tissues with the highest expression in testis. Hypoxia inducible factor-1 (HIF-1) is a transcriptional complex, consisting of an alpha and beta subunit, which plays a key role in coordinating the cellular response to hypoxia. During normal oxygen conditions, the alpha subunit of HIF-1 is rapidly degraded, however when hypoxia occurs this degradation is suppressed and HIF-1 activates the transcription of various genes important for survival and adaptation to hypoxia. Prolyl hydroxylase 2 catalyses the hydroxylation of specific prolyl residues within the HIF-1 alpha subunit, thereby targeting this subunit for degradation. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Versandbedingungen:
- Ambient