BNUB3025
Lymphocyte Specific Protein 1 (LSP1) / pp52(LSP1/3025), 0.2mg/mL
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- BNUB3025
- Zusätzliche Namen:
- WP34; pp52; lymphocyte specific protein 1; leukocyte specific protein 1
- Anwendung:
- IHC-P
- Konzentration:
- 0.2 mg/ml
- Molekulargewicht:
- 52 kDa
- Quelle:
- Animal
- Lagerbedingungen:
- 2-8[o]C, RT
- Hersteller:
- Biotium
- Host:
- Mouse
- Reaktivitäten:
- Human
- Buffer:
- PBS, 0.05% BSA, 0.05% azide|PBS, 0.05% BSA, 0.05% sodium azide
- Immunogen:
- Recombinant fragment of human LSP1 protein (around aa174-278) (exact sequence is proprietary)
- Formulierung:
- PBS, 0.05% BSA, 0.05% azide
- Klon:
- LSP1/3025
- Uniprot:
- P33241
- Synonyme:
- 47 kDa actin binding protein;47 kDa actin-binding protein;52 kDa phosphoprotein;adipose tissue-specific secretory factor;ADSF;C/EBP-epsilon regulated myeloid-specific secreted cysteine-rich protein precursor 1;c/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein;cysteine-rich secreted protein A12-alpha-like 2;cysteine-rich secreted protein FIZZ3;F-actin binding and cytoskeleton associated protein;FIZZ3;found in inflammatory zone 3;leufactin (leukocyte F-actin binding protein);leukocyte-specific protein 1;lymphocyte-specific antigen WP34;lymphocyte-specific protein 1;pp52;resistin;resistin delta2;RETN1;RSTN;WP34;XCP1
- Weitere Details:
- LSP1 is a hematopoietic-expressed gene that encodes an F-actin-binding, leukocyte-specific (including B and T lymphocytes, granulocytes and macrophages), phosphoprotein. However, mRNA splice variants that do not encode the lympho-specific protein are expressed from this gene in nonlymphoid cell lines as well (myocytes, stromal cells and fibroblasts), suggesting pp52 has a divergent role in signal transduction. The pp52 (LSP1) locus maps to human chromosome 11p15. 5, which is implicated in tumor-related chromosomal translocations found in chronic lymphocytic leukemia. The pp52 promoter contains key elements that control transcriptional activity including an initiator specifying the unique 5' terminus of pp52 mRNA, tandem pairs of Ets and SP1 motifs, and a single C/EBP motif. LSP1 binds the cytoskeleton and has been implicated in affecting cytoskeletal remodeling in a variety of leukocyte functions, including cell motility and chemotaxis. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Versandbedingungen:
- Ambient