BNUB2366
CD269 / TNFRSF17 / BCMA (B-Cell Maturation Protein) (BCMA/2366), 0.2mg/mL
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- BNUB2366
- Zusätzliche Namen:
- B-cell maturation protein; BCMA; CD269; TNR17; Tumor necrosis factor receptor superfamily member 17 (TNFRSF17)
- Anwendung:
- IHC-P
- Konzentration:
- 0.2 mg/ml
- Molekulargewicht:
- 20 kDa
- Quelle:
- Animal
- Lagerbedingungen:
- 2-8[o]C, RT
- Hersteller:
- Biotium
- Host:
- Mouse
- Reaktivitäten:
- Bovine, Human, Mouse
- Buffer:
- PBS, 0.05% BSA, 0.05% azide|PBS, 0.05% BSA, 0.05% sodium azide
- Immunogen:
- Recombinant human CD269 protein fragment (around aa 78-184) (exact sequence is proprietary)
- Formulierung:
- PBS, 0.05% BSA, 0.05% azide
- Klon:
- BCMA/2366
- Uniprot:
- Q02223
- Synonyme:
- B cell maturation antigen;B-cell maturation factor;B-cell maturation protein;BCM;BCMA;CD269;GABA(A) receptor subunit alpha-3;GABA(A) receptor, alpha 3;gamma-aminobutyric acid (GABA) A receptor, alpha 3;gamma-aminobutyric acid receptor subunit alpha-3;gamma-aminobutyric acid type A receptor alpha3 subunit;gamma-animobutyric acid (GABA) A receptor, alpha 3;TNFRSF13A;tumor necrosis factor receptor superfamily member 17
- Weitere Details:
- The B cell maturation protein (BCMA) is a type I integral membrane protein that belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is expressed as a 184 amino acid peptide that is expressed only in mature B-lymphocytes and is located on the cis part of the Golgi apparatus. BCMA shares significant homology with TACI (transmembrane activator) within the cysteine-rich domain. TACI has been shown to bind CAML, which induces activation of NFAT (nuclear factor of activated T cells). Both BCMA and TACI have been shown to bind APRIL and TALL-1, which stimulate B cell proliferation in conjunction with other B-cell activators. When overexpressed, TALL-1 stimulates the development of systemic lupus erythaematosus (SLE).Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Versandbedingungen:
- Ambient