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  2. Monoclonal

BNUB2199

Cytochrome p450(M12P4H2), 0.2mg/mL

Eine Lieferung in diese Region ist nicht möglich.

SKU:
BNUB2199
Zusätzliche Namen:
4-nitrophenol 2-hydroxylase; CPE1; CYP2Ecytochrome P450 2E1; CYPIIE1; cytochrome P450; family 2; subfamily E; polypeptide 1; cytochrome P450; subfamily IIE (ethanol-inducible); polypeptide 1 ; Cytochrome P450-J; EC 1.14.13; EC 1.14.13.n7; EC 1.14.14.1; flavoprotein-linked monooxygenase; microsomal monooxygenase; P450C2E; P450-J; xenobiotic monooxygenase
Anwendung:
IHC-P
Konzentration:
0.2 mg/ml
Molekulargewicht:
~50-55 kDa
Quelle:
Animal
Lagerbedingungen:
2-8[o]C, RT
Hersteller:
Biotium
Host:
Mouse
Reaktivitäten:
Bovine, Human, Mouse
Buffer:
PBS, 0.05% BSA, 0.05% azide|PBS, 0.05% BSA, 0.05% sodium azide
Immunogen:
Ovalbumin-conjugated synthetic peptide HIGFGCIPPR (C-terminal sequence)
Formulierung:
PBS, 0.05% BSA, 0.05% azide
Klon:
M12P4H2
Uniprot:
P05181
Synonyme:
4-nitrophenol 2-hydroxylase;CARP;CPE1;CYP2E;CYPIIE1;cytochrome P450 2E1;cytochrome P450-J;cytochrome P450, family 2, subfamily E, polypeptide 1;cytochrome P450, subfamily IIE (ethanol-inducible), polypeptide 1;flavoprotein-linked monooxygenase;microsomal monooxygenase;P450-J;P450C2E;xenobiotic monooxygenase
Weitere Details:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases, which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines, which are pre-mutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Versandbedingungen:
Ambient