Skip to content

Datenblatt herunterladen

download
  1. Alles ansehen
  2. Monoclonal

BNUB1656

HLA-DP/-DQ/-DR (MHC II)(CR3/43), 0.2mg/mL

Eine Lieferung in diese Region ist nicht möglich.

SKU:
BNUB1656
Zusätzliche Namen:
HLA-DPB1; HLA-DQA1; HLA-DQB1; HLA-DRA; HLA-DRB1; HLA-DRB3; HLA-DRB4; HLA-DRB5
Anwendung:
Flow Cytometry, WB, IHC-P, IF
Konzentration:
0.2 mg/ml
Molekulargewicht:
36 kDa (? chain) and 27 kDa (? chain)
Quelle:
Animal
Lagerbedingungen:
2-8[o]C, RT
Hersteller:
Biotium
Host:
Mouse
Reaktivitäten:
Bovine, Human, Mouse
Buffer:
PBS, 0.05% BSA, 0.05% azide|PBS, 0.05% BSA, 0.05% sodium azide
Immunogen:
Cells from human tonsil
Formulierung:
PBS, 0.05% BSA, 0.05% azide
Klon:
CR3/43
Uniprot:
P01903, P01908, P01909, P01920, P04440
Synonyme:
CELIAC1;DC-1 alpha chain;DC-alpha;DPB1;DQ-A1;DQA1;histocompatibility antigen HLA-DR alpha;HLA class II histocompatibility antigen DQ alpha chain;HLA class II histocompatibility antigen, DP beta 1 chain;HLA class II histocompatibility antigen, DP(W4) beta chain;HLA class II histocompatibility antigen, DQ alpha 1 chain;HLA class II histocompatibility antigen, DQ beta 1 chain;HLA class II histocompatibility antigen, DR alpha chain;HLA-DCA;HLA-DP;HLA-DP histocompatibility type, beta-1 subunit;HLA-DP1B;HLA-DPB;HLA-DQA;HLA-DQB;HLA-DRA1;IDDM1;MHC class II antigen DPB1;MHC class II antigen DQA1;MHC class II antigen DQB1;MHC class II antigen DRA;MHC class II antigen HLA-DQ-beta-1;MHC class II DQ alpha chain;MHC class II DQ beta chain;MHC class II DQA1;MHC class II HLA-DP-beta-1;MHC class II HLA-DQ beta glycoprotein;MHC class II HLA-DQ-alpha-1;MHC class II protein;MHC HLA DPB1;MHC HLA-DQ alpha;truncated MHC class II antigen
Weitere Details:
Reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DP, -DQ and -DR. Human MHC class II antigens are transmembrane glycoproteins composed of an chain (36 kDa) and a chain (27 kDa). They are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, and thymic epithelial cells and are also present on activated T lymphocytes. Human MHC class II genes are located in the HLA-D region that encodes at least six and ten chain genes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They, therefore, have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Versandbedingungen:
Ambient