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  2. Monoclonal

BNUB1638

CD257 / BAFF / TNFSF13B (C257/1638), 0.2mg/mL

Eine Lieferung in diese Region ist nicht möglich.

SKU:
BNUB1638
Zusätzliche Namen:
ApoL related ligand TALL 1; B lymphocyte stimulator; B-cell-activating factor; BAFF; BLyS; CD257; Dendritic cell-derived TNF-like molecule; DTL; PRO738; TALL-1; THANK; TNFSF13B; TNFSF20; Tumor necrosis factor ligand superfamily member 13b; Tumor necrosis factor ligand superfamily member 20; ZTNF4
Konzentration:
0.2 mg/ml
Molekulargewicht:
31 kDa (Monomer)
Quelle:
Animal
Lagerbedingungen:
2-8[o]C, RT
Hersteller:
Biotium
Host:
Mouse
Reaktivitäten:
Bovine, Human, Mouse
Buffer:
PBS, 0.05% BSA, 0.05% azide|PBS, 0.05% BSA, 0.05% sodium azide
Immunogen:
Purified recombinant human full-length CD257 protein
Formulierung:
PBS, 0.05% BSA, 0.05% azide
Klon:
C257/1638
Uniprot:
Q9Y275
Synonyme:
ApoL related ligand TALL-1;B lymphocyte stimulator;B-cell-activating factor;B-lymphocyte stimulator;BAFF;BLYS;CD257;delta BAFF;Delta4 BAFF;dendritic cell-derived TNF-like molecule;DTL;epididymis secretory sperm binding protein;TALL-1;TALL1;THANK;TNF and ApoL-related leukocyte expressed ligand 1;TNF homolog that activates apoptosis;TNF- and APOL-related leukocyte expressed ligand 1;TNFSF20;TNLG7A;tumor necrosis factor (ligand) superfamily, member 13b;tumor necrosis factor (ligand) superfamily, member 20;tumor necrosis factor ligand 7A;tumor necrosis factor ligand superfamily member 13B;tumor necrosis factor superfamily member 13b;tumor necrosis factor-like protein ZTNF4;ZTNF4
Weitere Details:
BAFF/CD257 is a type II transmembrane protein, and a member of the tumor necrosis factor ligand superfamily. It is proteolytically cleaved to form a soluble protein. BAFF, like other TNF ligand family members, forms homo-trimers. The predicted molecular weight of a BAFF monomer is approximately 31 kDa. It is expressed on peripheral blood B and T lymphocytes, monocytes, macrophages, and dendritic cells and is upregulated by IFN-gamma and down-regulated by PMA/ionomycin treatment. BAFF stimulates B and T cell immunity and regulates humoral immunity by binding TACI and BCMA receptors; BAFF prevents apoptosis and promotes B cell survival by binding the BAFF-specific receptor (BAFFR/BR3). Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Versandbedingungen:
Ambient