BNUB1361
Topoisomerase II alpha (Proliferation & Drug-Resistance Marker) (TOP2A/1361), 0.2mg/mL
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- BNUB1361
- Zusätzliche Namen:
- ATP hydrolyzing DNA topoisomerase II alfa; DNA gyrase; DNA topoisomerase (ATP hydrolyzing); DNA topoisomerase 2 alpha; DNA topoisomerase II 170kD; DNA topoisomerase II alpha; DNA Topoisomerase2; TOP2A; Topoisomerase DNA II alpha 170kDa; TP2A
- Anwendung:
- WB, IHC-P, IF
- Konzentration:
- 0.2 mg/ml
- Molekulargewicht:
- 170 kDa
- Quelle:
- Animal
- Lagerbedingungen:
- 2-8[o]C, RT
- Hersteller:
- Biotium
- Host:
- Mouse
- Reaktivitäten:
- Bovine, Human, Mouse
- Buffer:
- PBS, 0.05% BSA, 0.05% azide|PBS, 0.05% BSA, 0.05% sodium azide
- Immunogen:
- Recombinant human Topoisomerase II alpha fragment (aa1352-1493) (exact sequence is proprietary)
- Formulierung:
- PBS, 0.05% BSA, 0.05% azide
- Klon:
- TOP2A/1361
- Uniprot:
- P11388
- Synonyme:
- DNA gyrase;DNA topoisomerase (ATP-hydrolyzing);DNA topoisomerase 2-alpha;DNA topoisomerase II, 170 kD;DNA topoisomerase II, alpha isozyme;TOP2;TOP2alpha;TOPIIA;topoisomerase (DNA) II alpha 170kDa;TP2A
- Weitere Details:
- This antibody recognizes a 170 kDa protein, which is identified as topoisomerase IIA Alpha. It shows no cross-reaction with topoisomerase IIB Beta or topoisomerase I. Topo IIA Alpha plays important roles in synthesis and transcription of DNA as well as chromosomal segregation during mitosis. It is reported to be a sensitive and specific marker of late S-, G2- & M-phases in transformed and developmentally regulated normal cells. Topo IIA Alpha is also implicated in drug resistance of tumor cells.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Versandbedingungen:
- Ambient