BNUB1320
Protocadherin FAT2 (FAT Atypical Cadherin 2) (8C5), 0.2mg/mL
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- BNUB1320
- Zusätzliche Namen:
- FAT tumor suppressor homolog 2 (HFAT2); cadherin family member 8 (CDHF8); cadherin-related family member 9 (CDHR9); multiple EGF-like domains protein 1; multiple epidermal growth factor-like domains 1 (MEGF1); multiple epidermal growth factor-like domains protein 1; protocadherin FAT2
- Anwendung:
- IHC-P
- Konzentration:
- 0.2 mg/ml
- Molekulargewicht:
- 480 kDa
- Quelle:
- Animal
- Lagerbedingungen:
- 2-8[o]C, RT
- Hersteller:
- Biotium
- Host:
- Mouse
- Reaktivitäten:
- Bovine, Human, Mouse
- Buffer:
- PBS, 0.05% BSA, 0.05% azide|PBS, 0.05% BSA, 0.05% sodium azide
- Immunogen:
- Purified recombinant human FAT2 fusion protein
- Formulierung:
- PBS, 0.05% BSA, 0.05% azide
- Klon:
- 8C5
- Uniprot:
- Q9NYQ8
- Synonyme:
- cadherin family member 8;cadherin-related family member 9;CDHF8;CDHR9;FAT tumor suppressor homolog 2;HFAT2;MEGF1;multiple EGF-like domains protein 1;multiple epidermal growth factor-like domains 1;multiple epidermal growth factor-like domains protein 1;protocadherin Fat 2;protocadherin FAT2;SCA45
- Weitere Details:
- This antibody recognizes a protein of 480 kDa, which is identified as FAT2. The cadherins represent a family of Ca2 -dependent adhesion molecules that function to mediate cell-to-cell binding that is critical for the maintenance of structure and morphogenesis. Cadherins each contain a large extracellular domain at the N-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short C-terminal intracellular domain interacts with a variety of cytoplasmic proteins, including beta-catenin, to regulate cadherin function. The cadherin superfamily includes cadherins, protocadherins, desmogleins and desmocollins. FAT2 (FAT tumor suppressor homolog 2) is a single-pass type I membrane protein that belongs to the protocadherin subfamily of cadherins. FAT2 contains one Laminin G-like domain, two EGF-like domains and 32 cadherin domains and is believed to function as a cell adhesion molecule, controlling cell proliferation and playing an important role in cerebellum development. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Versandbedingungen:
- Ambient