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BNUB1282

ETS1 / (Marker of Tumor Metastasis) (ETS1/1282), 0.2mg/mL

Eine Lieferung in diese Region ist nicht möglich.

SKU:
BNUB1282
Zusätzliche Namen:
Avian erythroblastosis virus E26 (v ets) oncogene homolog 1; ETS1; EWSR2; p54; v-ets erythroblastosis virus E26 oncogene homolog 1
Konzentration:
0.2 mg/ml
Molekulargewicht:
54 kda
Quelle:
Animal
Lagerbedingungen:
2-8[o]C, RT
Hersteller:
Biotium
Host:
Mouse
Reaktivitäten:
Bovine, Human, Mouse
Buffer:
PBS, 0.05% BSA, 0.05% azide|PBS, 0.05% BSA, 0.05% sodium azide
Immunogen:
Recombinant human ETS1 fragment (aa137-230) (exact sequence is proprietary)
Formulierung:
PBS, 0.05% BSA, 0.05% azide
Klon:
ETS1/1282
Uniprot:
P14921
Synonyme:
Avian erythroblastosis virus E26 (v-ets) oncogene homolog-1;c-ets-1;ETS-1;EWSR2;p54;protein C-ets-1;v-ets avian erythroblastosis virus E2 oncogene homolog 1;v-ets avian erythroblastosis virus E26 oncogene homolog 1
Weitere Details:
ETS1 proto-oncogene is an important transcription factor that plays a role in cell proliferation and differentiation. ETS1 is related to the growth of carcinoma cells by its regulation of the transcription of matrix metalloproteinases and urokinase-type plasminogen activator. The processes of tumor invasion and metastasis depend on the increased proteolytic activity of the invading tumor cells that may involve matrix metalloproteinases, cathepsins B and D and plasminogen activator in the metastatic cascade. ETS1 is preferentially expressed in lymphoid cells, where it is essential for the maintenance of the normal pool of resting T and B cells. ETS1 expression level and distribution are differentially controlled in resting, activated and apoptotic lymphocytes.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Versandbedingungen:
Ambient