BNUB1253
Neurofilament, phospho (NF-H) (Neuronal Marker)(NE14), 0.2mg/mL
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- BNUB1253
- Zusätzliche Namen:
- NEFH; Neurofilament H; Neurofilament Heavy Polypeptide 200kDa; Neurofilament Triplet H Protein; NF-H; NF200
- Anwendung:
- Flow Cytometry, WB, IHC-P
- Konzentration:
- 0.2 mg/ml
- Molekulargewicht:
- 200 kDa
- Quelle:
- Animal
- Lagerbedingungen:
- 2-8[o]C, RT
- Hersteller:
- Biotium
- Host:
- Mouse
- Reaktivitäten:
- Bovine, Human, Mouse, Porcine, Rabbit, Rat, Feline, Guinea Pig
- Buffer:
- PBS, 0.05% BSA, 0.05% azide|PBS, 0.05% BSA, 0.05% sodium azide
- Immunogen:
- Crude neurofilament preparation from porcine spinal cord
- Formulierung:
- PBS, 0.05% BSA, 0.05% azide
- Klon:
- NE14
- Uniprot:
- P12036
- Synonyme:
- 200 kDa neurofilament protein;CMT2CC;neurofilament heavy polypeptide;neurofilament triplet H protein;neurofilament, heavy polypeptide 200kDa;NF-H;NFH
- Weitere Details:
- This MAb reacts with a 200 kDa protein, identified as heavy sub-unit of neurofilaments (NF-H). It reacts specifically with the phosphorylated KSP/KEP segment at the C-terminus of the heavy subunit (NF-H) of neurofilaments. After dephosphorylation of neurofilaments with alkaline phosphatase, this Ab no longer binds. Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68 kDa (NF-L), 160 kDa (NF-M) and 200 kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.
- Versandbedingungen:
- Ambient