BNUB1095
HLA-A (MHC I) (108-2C5), 0.2mg/mL
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- BNUB1095
- Zusätzliche Namen:
- HLA-A; HLA class 1A; MHC class I HLA-A
- Anwendung:
- Flow Cytometry, IHC-Fr, IF, IP
- Konzentration:
- 0.2 mg/ml
- Molekulargewicht:
- ~41 kDa
- Quelle:
- Animal
- Lagerbedingungen:
- 2-8[o]C, RT
- Hersteller:
- Biotium
- Host:
- Mouse
- Reaktivitäten:
- Bovine, Human, Mouse
- Buffer:
- PBS, 0.05% BSA, 0.05% azide|PBS, 0.05% BSA, 0.05% sodium azide
- Immunogen:
- Normal human peripheral blood lymphocytes
- Formulierung:
- PBS, 0.05% BSA, 0.05% azide
- Klon:
- 108-2C5
- Uniprot:
- P01889, P30443, P30499
- Synonyme:
- AS;ATP-citrate (pro-S-)-lyase;ATP-citrate synthase;B-4901;CELE_F46F6.2;citrate cleavage enzyme;HLA class I antigen HLA-B;HLA class I histocompatibility antigen, A alpha chain;HLA class I histocompatibility antigen, A-1 alpha chain;HLA class I histocompatibility antigen, B alpha chain;HLAA;HLAB;Human leukocyte antigen B;leukocyte antigen class I-A;leukocyte antigen class I-B;major histocompatibility complex, class I, B;MHC class 1 antigen;MHC class I antigen A*1;MHC class I antigen B*7;MHC class I antigen Cw*1;MHC class I antigen HLA-A heavy chain;MHC class I antigen HLA-B alpha chain;MHC class I antigen HLA-B heavy chain;MHC class I antigen SHCHA;MHC class I molecule;MHC HLA-B cell surface glycoprotein;MHC HLA-B transmembrane glycoprotein;Protein kinase C
- Weitere Details:
- HLA-A, with HLA-B and HLA-C, belongs to major histocompatibility complex (MHC) class I antigens and expresses constitutively on all nucleated cells. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation. This MAb is useful for HLA molecular typing of peripheral blood leukocytes as well as a large number of leukemic cell lines. It reacts with an intralocus determinant present on a limited number of HLA-A locus-encoded gene products (HLA-A2, -A3, -A28, -A29, -A30, -A31 and -Aw33). Its epitope maps between aa65-to-aa80 of thealpha1 domain of the HLA-A. This MAb recognizes an intralocus determinant present on a limited number of HLA-A locus-encoded gene products (HLA-A2, -A3, A28, -A29, -A30, -A31 and -Aw33). Furthermore, by testing its reactivity with HLA-A2 natural variants and mutants, the importance of amino acid residues 79 and/or 80 of thealpha1 domain was demonstrated in the formation of an intralocus HLA-A determinant.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Versandbedingungen:
- Ambient