BNUB0743
Mucin 1 / EMA / Episialin / CD227(GP1.4 + E29), 0.2mg/mL
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- BNUB0743
- Zusätzliche Namen:
- Breast carcinoma-associated antigen DF3; CA15-3; Carcinoma-associated mucin Episialin; Epithelial Membrane Antigen; H23AG; KL-6; MAM6; MUC-1; MUC-1/SEC; MUC-1/X; MUC1-alpha; MUC1-beta; MUC1-CT; MUC1-NT; MUC1/ZD; Mucin 1 cell surface associated; Mucin-1 subunit beta; Peanut-reactive urinary mucin; PEM; PEMT; Polymorphic epithelial mucin; PUM; Tumor-associated epithelial membrane antigen
- Anwendung:
- IHC-P
- Konzentration:
- 0.2 mg/ml
- Molekulargewicht:
- 265-400 kDa
- Quelle:
- Animal
- Lagerbedingungen:
- 2-8[o]C, RT
- Hersteller:
- Biotium
- Host:
- Mouse
- Reaktivitäten:
- Bovine, Human, Mouse
- Buffer:
- PBS, 0.05% BSA, 0.05% azide|PBS, 0.05% BSA, 0.05% sodium azide
- Immunogen:
- Human milk fat globule membranes (GP1.4); Delipidated extract of human milk fat globule membranes (E29)
- Formulierung:
- PBS, 0.05% BSA, 0.05% azide
- Klon:
- GP1.4 E29
- Uniprot:
- P15941
- Synonyme:
- ADMCKD;ADMCKD1;ADTKD2;breast carcinoma-associated antigen DF3;CA 15-3;cancer antigen 15-3;carcinoma-associated mucin;CD227;EMA;episialin;H23 antigen;H23AG;KL-6;krebs von den Lungen-6;MAM6;MCD;MCKD;MCKD1;MUC-1;MUC-1/SEC;MUC-1/X;MUC1/ZD;mucin 1, transmembrane;mucin-1;peanut-reactive urinary mucin;PEM;PEMT;polymorphic epithelial mucin;PUM;tumor associated epithelial mucin;tumor-associated epithelial membrane antigen;Tumor-associated mucin
- Weitere Details:
- In Western blotting, it recognizes proteins in MW range of 265-400 kDa, identified as different glycoforms of EMA. The A Alpha subunit has cell adhesive properties. It can act both as an adhesion and an anti-adhesion protein. EMA may provide a protective layer on epithelial cells against bacterial and enzyme attack. The B Beta subunit contains a C-terminal domain, which is involved in cell signaling, through phosphorylations and protein-protein interactions. In immunohistochemical assays, it superbly stains routine formalin/paraffin carcinoma tissues. Antibody to EMA is useful as a pan-epithelial marker for detecting early metastatic loci of carcinoma in bone marrow or liver.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Versandbedingungen:
- Ambient