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  2. Monoclonal

BNCB0276

TAG-72 / CA72.4(B72.3), Biotin conjugate, 0.1mg/mL

Eine Lieferung in diese Region ist nicht möglich.

SKU:
BNCB0276
Zusätzliche Namen:
CA72.4, Tumor associated glycoprotein 72
Anwendung:
Flow Cytometry, RIA, WB, IHC-P, IP
Konzentration:
0.1 mg/ml
Molekulargewicht:
220 kDa
Quelle:
Animal
Lagerbedingungen:
2-8[o]C, RT
Hersteller:
Biotium
Host:
Mouse
Reaktivitäten:
Bovine, Canine, Hamster, Human, Mouse, Rat
Buffer:
0.05% sodium azide|PBS, 0.1% BSA, 0.05% azide
Immunogen:
Membrane-enriched fraction of a human breast carcinoma liver metastasis
Formulierung:
PBS, 0.1% BSA, 0.05% azide
Klon:
B72.3
Synonyme:
CELE_C25A1.3;mRNA cap guanine-N7 methyltransferase
Weitere Details:
Recognizes an oncofetal antigen of 220 kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This MAb defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80% sensitivity and 93% specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of anti-TAG-72 and anti-GCDFP-15 is valuable in the diagnosis of apocrine carcinoma.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Versandbedingungen:
Ambient