BNCB0008
MAGE A1(MA454), Biotin conjugate, 0.1mg/mL
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- BNCB0008
- Zusätzliche Namen:
- MZ2 E, cancer/testis antigen 1.1, CT1.1, MAGE1A, MAGEA1, Melanoma antigen family A 1, Melanoma associated antigen 1, Melanoma associated antigen MZ2 E
- Anwendung:
- ELISA, Flow Cytometry, WB, IHC-P
- Konzentration:
- 0.1 mg/ml
- Molekulargewicht:
- 42-46 kDa
- Quelle:
- Animal
- Lagerbedingungen:
- 2-8[o]C, RT
- Hersteller:
- Biotium
- Host:
- Mouse
- Reaktivitäten:
- Bovine, Canine, Human, Mouse, Rat
- Buffer:
- 0.05% sodium azide|PBS, 0.1% BSA, 0.05% azide
- Immunogen:
- Human MAGE-A1 full length recombinant protein
- Formulierung:
- PBS, 0.1% BSA, 0.05% azide
- Klon:
- MA454
- Uniprot:
- P43355
- Synonyme:
- antigen MZ2-E;cancer/testis antigen 1.1;cancer/testis antigen family 1, member 1;CT1.1;MAGE-1 antigen;MAGE1;melanoma antigen family A 1;melanoma antigen family A, 1 (directs expression of antigen MZ2-E);melanoma antigen family A1;melanoma antigen MAGE-1;melanoma-associated antigen 1;melanoma-associated antigen MZ2-E
- Weitere Details:
- Recognizes a protein of 42-46 kDa, identified as MAGE-1. This MAb does not cross-react with MAGE-2, -3, -4, -6 -9, -10, -or -12 protein. Human malignant neoplasms carry rejection antigens that are recognized by the patients' autologous, tumor directed and specific, cytolytic, CD8 T lymphocyte clones (CTL). The MAGE family of genes codes an important group of antigens. It was identified that melanomas and primary glial brain tumors express common melanoma associated antigens (MAAs). Because MAGE-1 is expressed on a significant proportion of human neoplasms of various histological types (melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian, renal cell carcinomas) and not on normal tissues, the encoded antigen may serve as a marker of early detection and target for cancer immunotherapy. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Versandbedingungen:
- Ambient