BNC942961
C1QB / Complement C1q B-Chain(C1QB/2961), CF594 conjugate, 0.1mg/mL
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- BNC942961
- Zusätzliche Namen:
- C1QB; Complement component 1 q subcomponent B chain; Complement component C1q B chain
- Anwendung:
- IHC-P
- Konzentration:
- 0.1 mg/ml
- Molekulargewicht:
- 26-29 kDa
- Quelle:
- Animal
- Lagerbedingungen:
- 2-8[o]C, RT
- Hersteller:
- Biotium
- Host:
- Mouse
- Reaktivitäten:
- Bovine, Human, Mouse
- Buffer:
- 0.05% sodium azide|PBS, 0.1% BSA, 0.05% azide
- Immunogen:
- Recombinant fragment (around aa 41-188) of human C1QB protein (exact sequence is proprietary)
- Formulierung:
- PBS, 0.1% BSA, 0.05% azide
- Klon:
- C1QB/2961
- Uniprot:
- P02746
- Synonyme:
- 90 kDa ribosomal protein S6 kinase 4;complement C1q chain B;complement C1q subcomponent subunit B;complement component 1, q subcomponent, B chain;complement component 1, q subcomponent, beta polypeptide;complement component C1q, B chain;complement subcomponent C1q chain B;mitogen- and stress-activated protein kinase 2;MSK2;nuclear mitogen- and stress-activated protein kinase 2;ribosomal protein kinase B;ribosomal protein S6 kinase alpha-4;ribosomal protein S6 kinase, 90kDa, polypeptide 4;RSK-B;S6K-alpha-4
- Weitere Details:
- Complement C1q B Chain (C1qb) is a subunit of C1q. C1q is composed of 6 polypeptide chains each of C1qa, C1qb, and C1qc. C1q is a component of the classical complement pathway, and thereby plays an important role in the immune response. Each C1q subunit contains an N-terminal collagen-like region and a C-terminal C1q globular domain. The presence of receptors for C1q on effector cells modulates its activity, which may be antibody-dependent or independent. Macrophages are the primary source of C1q, while anti-inflammatory drugs as well as cytokines differentially regulate expression of the mRNA as well as the protein. C1q deficiency is associated with lupus erythematosus and glomerulonephritis. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Versandbedingungen:
- Ambient