BNC940977
TGF-beta(1D11.16.8), CF594 conjugate, 0.1mg/mL
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- BNC940977
- Zusätzliche Namen:
- GP40; Leu9; p41; T-cell leukemia antigen; T-cell surface antigen Leu-9; Tp40; TP41
- Anwendung:
- IHC-P, FuncS
- Konzentration:
- 0.1 mg/ml
- Molekulargewicht:
- ~13 kDa
- Quelle:
- Animal
- Lagerbedingungen:
- 2-8[o]C, RT
- Hersteller:
- Biotium
- Host:
- Mouse
- Reaktivitäten:
- Bovine, Canine, Hamster, Human, Mouse, Rat
- Buffer:
- 0.05% sodium azide|PBS, 0.1% BSA, 0.05% azide
- Immunogen:
- Bovine TGF-beta2 protein
- Formulierung:
- PBS, 0.1% BSA, 0.05% azide
- Klon:
- 1D11.16.8
- Uniprot:
- P01137, P10600, P61812
- Synonyme:
- ARVD;ARVD1;BSC-1 cell growth inhibitor;CED;cetermin;DPD1;G-TSF;glioblastoma-derived T-cell suppressor factor;IBDIMDE;LAP;latency-associated peptide;LDS4;LDS5;polyergin;prepro-transforming growth factor beta-1;prepro-transforming growth factor beta-2;prepro-transforming growth factor beta-3;RNHF;TGF-beta-1;TGF-beta1;TGF-beta2;TGF-beta3;TGFB;TGFbeta;transforming growth factor beta-1 proprotein;transforming growth factor beta-2 proprotein;transforming growth factor beta-3 proprotein;transforming growth factor beta1
- Weitere Details:
- This MAb recognizes TGF beta 1, 2 and 3. Three TGF-betas have been identified in mammals. TGF-beta1, TGF-beta2 and TGF-beta3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecules. Biologically active TGF-beta requires dimerization of the monomers (usually homodimers) and release of the latent peptide portion. Overall, the mature region of the TGF-beta3 protein has approximately 80% identity to the mature region of both TGF-beta1 and TGF-beta2. However, the NH2 terminals or precursor regions of their molecules share only 27% sequence identity. TGF-beta's inhibit the growth of epithelial cells and stimulate the growth of mesenchymal cells.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Versandbedingungen:
- Ambient