CD19 (B-Lymphocyte Marker)(CD19/3117), CF488A conjugate, 0.1mg/mL

Eine Lieferung in diese Region ist nicht möglich.

SKU:: BNC883117
Zusätzliche Namen:: B-lymphocyte antigen CD19; B-lymphocyte surface antigen B4; CVID3; Leu-12; T-cell surface antigen Leu-12
Anwendung:: IHC-P
Konzentration:: 0.1 mg/ml
Molekulargewicht:: 95 kDa
Quelle:: Animal
Lagerbedingungen:: 2-8[o]C, RT
Hersteller:: Biotium
Host:: Mouse
Reaktivitäten:: Human
Buffer:: 0.05% sodium azide|PBS, 0.1% BSA, 0.05% azide
Immunogen:: Recombinant fragment of human CD19 protein (around aa96-281) (exact sequence is proprietary)
Formulierung:: PBS, 0.1% BSA, 0.05% azide
Klon:: CD19/3117
Uniprot:: P15391
Synonyme:: B-lymphocyte antigen CD19;B-lymphocyte surface antigen B4;B4;CVID3;differentiation antigen CD19;T-cell surface antigen Leu-12
Weitere Details:: CD19 is a transmembrane glycoprotein that contains two extracellular immunoglobulin-like domains. CD19 is present in both benign and malignant B-cells and is considered to be the most reliable surface marker of this lineage over a wide range of maturational stages. In normal lymphoid tissue, CD19 is observed in germinal centers, in mantle zone cells, and in scattered cells of the inter-follicular areas. Anti-CD19 exhibits an overall immunoreactivity pattern similar to those of the antibodies against CD20 and CD22. However, in contrast to CD20, expression of CD19 is continuous throughout B-cell development and through terminal differentiation of B-cells into plasma cells. Anti-CD19 positivity is seen in the vast majority of B-cell neoplasms commonly at a lower intensity than normal B-cell counterparts. Plasma cell neoplasms are nearly always negative, as are T-cell neoplasms. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Versandbedingungen:: Ambient