BNC882002
PD1, Mouse(RMP1-14), CF488A conjugate, 0.1mg/mL
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- BNC882002
- Zusätzliche Namen:
- CD279; CD279 antigen; PD1; PDCD1; Programmed cell death 1; Programmed cell death protein 1; Systemic lupus erythematosus susceptibility 2 (SLEB2)
- Anwendung:
- Flow Cytometry, FuncS
- Konzentration:
- 0.1 mg/ml
- Molekulargewicht:
- ~50-55 kDa
- Quelle:
- Animal
- Lagerbedingungen:
- 2-8[o]C, RT
- Hersteller:
- Biotium
- Host:
- Rat
- Reaktivitäten:
- Bovine, Mouse, Rat
- Buffer:
- 0.05% sodium azide|PBS, 0.1% BSA, 0.05% azide
- Immunogen:
- PDCD1 transfected BHK cells
- Formulierung:
- PBS, 0.1% BSA, 0.05% azide
- Klon:
- RMP1-14
- Uniprot:
- Q02242
- Synonyme:
- ATP receptor;Ly101;mPD-1;P2X purinoceptor 3;P2X receptor, subunit 3;P2X3;PD-;PD-1;Pdc;Pdc1;programmed cell death 1 protein;programmed cell death protein 1;protein PD-1;purinergic receptor P2X, ligand gated ion channel, 3;purinergic receptor P2X3;purinoceptor P2X3
- Weitere Details:
- PD-1 is expressed on a subset of CD4-CD8-thymocytes, and on activated T and B cells. PD-1 is thought to be involved in lymphocyte clonal selection and peripheral tolerance. The PD-1 ligands, PD-L1 (also known as B7-H1) and PD-L2 (B7-DC), are members of the B7 immunoglobulin superfamily. PD-1 is transiently expressed on CD4 and CD8 thymocytes as well as activated T and B-lymphocytes and myeloid cells. Additionally, Pdcd1mRNA is expressed in developing B-lymphocytes during the pro-B-cell stage. The RMP1-14 antibody has been reported to block the binding of PD-1 to its ligands (B7-H1 and B7-DC) and to inhibit T cell proliferation and cytokine production co-stimulated by macrophages (but not by dendritic cells and B cells). Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Versandbedingungen:
- Ambient