PDCD1 / PD1 / CD279 (Programmed Cell Death 1), CF488A conjugate, 0.1mg/mL

Eine Lieferung in diese Region ist nicht möglich.

SKU:: BNC881457
Zusätzliche Namen:: CD279; hPD-1; hSLE1; PD1; PDCD1; Programmed Cell Death Protein 1; Protein PD-1; SLEB2; Systemic lupus erythematosus susceptibility 2
Anwendung:: IHC-P
Konzentration:: 0.1 mg/ml
Molekulargewicht:: 55 kDa
Quelle:: Animal
Lagerbedingungen:: 2-8[o]C, RT
Hersteller:: Biotium
Host:: Rabbit
Reaktivitäten:: Bovine, Human, Rabbit
Buffer:: 0.05% sodium azide|PBS, 0.1% BSA, 0.05% azide
Immunogen:: Human recombinant PDCD1 protein fragment
Formulierung:: PBS, 0.1% BSA, 0.05% azide
Uniprot:: Q15116
Synonyme:: 4930500O09Rik;C9orf138;CD279;FAM154A;family with sequence similarity 154, member A;hPD-1;hPD-l;hSLE1;PD-1;PD1;programmed cell death 1 protein;programmed cell death protein 1;protein FAM154A;protein PD-1;SLEB2;stabilizer of axonemal microtubules 1;systemic lupus erythematosus susceptibility 2
Weitere Details:: PDCD-1 (programmed cell death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD-1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD-1 is expressed by few B-cells, so anti-PDCD-1 may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma. In addition, PDCD-1 expression provides evidence that angioimmunoblastic lymphoma is a neoplasm derived from germinal center-associated T-cells. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Versandbedingungen:: Ambient