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  2. Monoclonal

BNC880831

Calponin-1(CALP), CF488A conjugate, 0.1mg/mL

Eine Lieferung in diese Region ist nicht möglich.

SKU:
BNC880831
Zusätzliche Namen:
Calponin-1; CNN1; Calponin 1 basic smooth muscle; Calponin H1 smooth muscle
Anwendung:
Flow Cytometry, WB, IHC-P, IF
Konzentration:
0.1 mg/ml
Molekulargewicht:
34 kda
Quelle:
Animal
Lagerbedingungen:
2-8[o]C, RT
Hersteller:
Biotium
Host:
Mouse
Reaktivitäten:
Bovine, Human, Mouse, Rat
Buffer:
0.05% sodium azide|PBS, 0.1% BSA, 0.05% azide
Immunogen:
Crude human uterus extract
Formulierung:
PBS, 0.1% BSA, 0.05% azide
Klon:
CALP
Uniprot:
P51911
Synonyme:
basic calponin;calponin 1, basic, smooth muscle;calponin H1, smooth muscle;calponin-1;calponins, basic;epididymis secretory protein Li 14;HEL-S-14;Sm-Calp;SMCC
Weitere Details:
Calponin is a calmodulin, F-actin and tropomyosin binding protein, which is thought to be involved in the regulation of smooth muscle contraction. Calponin expression is restricted to smooth muscle cells and has been shown to be a marker of the differentiated (contractile) phenotype of developing smooth muscle. Multiple isoelectric variants of calponin have been identified, however only two molecular weight isoforms exist, a 34 kDa form and a 29 kDa form. Expression of the 29 kDa form, I-calponin, is primarily restricted to muscle of the urogenital tract, whereas the higher molecular weight variant has been demonstrated in vascular and visceral smooth muscle. In Western blotting, this MAb reacts with only the 34 kDa form of calponin in extracts of human aortic medial smooth muscle and is unreactive with fibroblast extracts of cultivated human foreskin. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Versandbedingungen:
Ambient