BNC880495
SUMO-1(SM1/495), CF488A conjugate, 0.1mg/mL
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- BNC880495
- Zusätzliche Namen:
- GAP-modifying protein 1; GMP1; OFC10; PIC1; SENP2; Sentrin 1; Small ubiquitin-related modifier 1; SMT3; SMT3 suppressor of mif two 3 homolog 1; SMT3C; SMT3H3; Ubiquitin homology domain protein PIC1; Ubiquitin Like 1; Ubiquitin like protein UBL1
- Anwendung:
- Flow Cytometry, WB, IHC-P, IF
- Konzentration:
- 0.1 mg/ml
- Molekulargewicht:
- 11.5 kDa (Monomer); 90 kDa (Heteromer)
- Quelle:
- Animal
- Lagerbedingungen:
- 2-8[o]C, RT
- Hersteller:
- Biotium
- Host:
- Mouse
- Reaktivitäten:
- Bovine, Human, Mouse, Rat
- Buffer:
- 0.05% sodium azide|PBS, 0.1% BSA, 0.05% azide
- Immunogen:
- Recombinant human SUMO1 protein
- Formulierung:
- PBS, 0.1% BSA, 0.05% azide
- Klon:
- SM1/495
- Uniprot:
- P63165
- Synonyme:
- DAP1;GAP modifying protein 1;GAP-modifying protein 1;GMP1;OFC10;PIC1;SENP2;sentrin;small ubiquitin-related modifier 1;SMT3;SMT3 homolog 3;SMT3 suppressor of mif two 3 homolog 1;SMT3C;SMT3H3;ubiquitin-homology domain protein PIC1;ubiquitin-like protein SMT3C;ubiquitin-like protein UBL1;UBL1
- Weitere Details:
- This MAb is specific to SUMO-1 and shows no cross-reaction with either SUMO-2 or SUMO-3. The small ubiquitin-related modifier (SUMO) proteins, which include SUMO-1, SUMO-2 and SUMO-3, belong to the ubiquitin-like protein family. Like ubiquitin, the SUMO proteins are synthesized as precursor proteins that undergo processing before conjugation to target proteins. Also, both utilize the E1, E2, and E3 cascade enzymes for conjugation. However, SUMO and ubiquitin differ with respect to targeting. Ubiquitination predominantly targets proteins for degradation, whereas sumoylation targets proteins to a variety of cellular processing, including nuclear transport, transcriptional regulation, apoptosis and protein stability. The unconjugated SUMO-1 protein localizes to the nuclear membrane. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Versandbedingungen:
- Ambient