BNC880169
CD36(185-1G2), CF488A conjugate, 0.1mg/mL
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- BNC880169
- Zusätzliche Namen:
- Adipocyte membrane protein; CHDS7; Collagen receptor, platelet; fatty acid translocase (FAT); Fatty acid transport protein; glycoprotein iiib (GP IIIb); PAS IV; PAS-4; pas4 protein; platelet collagen receptor; Platelet glycoprotein 4; scarb3; Scavenger receptor class B member 3; thrombospondin receptor
- Anwendung:
- Flow Cytometry, IF, IP, FuncS
- Konzentration:
- 0.1 mg/ml
- Molekulargewicht:
- 80-90 kda
- Quelle:
- Animal
- Lagerbedingungen:
- 2-8[o]C, RT
- Hersteller:
- Biotium
- Host:
- Mouse
- Reaktivitäten:
- Bovine, Human, Mouse
- Buffer:
- 0.05% sodium azide|PBS, 0.1% BSA, 0.05% azide
- Immunogen:
- Stimulated human leukocytes
- Formulierung:
- PBS, 0.1% BSA, 0.05% azide
- Klon:
- 185-1G2
- Uniprot:
- P16671
- Synonyme:
- BDPLT10;CD36 antigen (collagen type I receptor, thrombospondin receptor);CD36 molecule (thrombospondin receptor);CHDS7;cluster determinant 36;FAT;fatty acid translocase;glycoprotein IIIb;GP3B;GP4;GPIIIB;GPIV;leukocyte differentiation antigen CD36;PAS IV;PAS-4;PAS-4 protein;PASIV;Platelet collagen receptor;platelet glycoprotein 4;platelet glycoprotein IV;SCARB3;scavenger receptor class B, member 3;Thrombospondin receptor
- Weitere Details:
- Recognizes a protein of 80 kDa-90 kDa, identified as CD36 (Workshop IV; Code P-26). Its epitope maps between aa155-183. It is expressed on platelets, monocytes and macrophages, microvascular endothelial cells, erythrocyte precursors, mammary epithelial cells, and some macrophage derived dendritic cells. CD36 acts as a receptor for thrombospondin (TSP), collagen types I, IV and V, P. falciparum malaria-infected erythrocytes, and sickle erythrocytes. It also functions as a scavenger receptor, mediating macrophage uptake of oxidized low-density lipoprotein (LDL) and recognition of apoptotic polymorphonuclear leukocytes (PMN). CD36 plays a role in platelet aggregation, macrophage foam cell development, inflammation, and the tissue ischemia observed in sickle cell disease and cerebral malaria. Note that 1-4% of Japanese and East Asia population lack CD36. This MAb blocks adhesion of P. falciparum parasitized red blood cells to CD36 and strongly inhibits collagen-induced platelet aggregation.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Versandbedingungen:
- Ambient