BNC880141
Alkaline Phosphatase(V17.1), CF488A conjugate, 0.1mg/mL
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- BNC880141
- Zusätzliche Namen:
- Alkaline phosphatase tissue non-specific; Alkaline phosphatase liver/bone/kidney; Alkaline phosphatase biomineralization associated; TNAP; TNALP; ALPL
- Anwendung:
- IHC-P
- Konzentration:
- 0.1 mg/ml
- Molekulargewicht:
- 55 kDa
- Quelle:
- Animal
- Lagerbedingungen:
- 2-8[o]C, RT
- Hersteller:
- Biotium
- Host:
- Mouse
- Reaktivitäten:
- Bovine, Human, Mouse
- Buffer:
- 0.05% sodium azide|PBS, 0.1% BSA, 0.05% azide
- Immunogen:
- Bovine intestinal alkaline phosphatase
- Formulierung:
- PBS, 0.1% BSA, 0.05% azide
- Klon:
- V17.1
- Uniprot:
- P05186, P05187, P09923, P10696
- Synonyme:
- alkaline phosphatase liver/bone/kidney isozyme;alkaline phosphatase Nagao isozyme;alkaline phosphatase Regan isozyme;alkaline phosphatase, germ cell type;alkaline phosphatase, liver/bone/kidney;alkaline phosphatase, placental like 2;alkaline phosphatase, placental type;alkaline phosphatase, placental-like;alkaline phosphatase, tissue-nonspecific isozyme;alkaline phosphomonoesterase;ALP;ALP-1;ALPI;ALPPL;ALPPL2;AP-TNAP;APTNAP;GCAP;germ cell alkaline phosphatase;glycerophosphatase;HOPS;HPPA;HPPC;HPPI;HPPO;IAP;intestinal alkaline phosphatase;intestinal-type alkaline phosphatase;Kasahara isozyme;liver/bone/kidney-type alkaline phosphatase;Nagao isozyme;PALP;placental alkaline phosphatase 1;Placental alkaline phosphatase-like;placental-like alkaline phosphatase;PLAP;PLAP-1;testicular and thymus alkaline phosphatase;tissue non-specific alkaline phosphatase;tissue-nonspecific ALP;TNALP;TNAP;TNSALP;uncharacterized protein LOC75431
- Weitere Details:
- This antibody reacts with tissue non-specific alkaline phosphatase. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypo-phosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Versandbedingungen:
- Ambient