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BNC740735

Human Lambda Light Chain(LcN-2 + ICO-106), CF740 conjugate, 0.1mg/mL

Eine Lieferung in diese Region ist nicht möglich.

SKU:
BNC740735
Zusätzliche Namen:
Bence Jones Protein; BJP; IGLC 1/2/3; Mcg Marker; Paraprotein
Anwendung:
WB
Konzentration:
0.1 mg/ml
Molekulargewicht:
~22.5 kDa
Quelle:
Animal
Lagerbedingungen:
2-8[o]C, RT
Hersteller:
Biotium
Host:
Mouse
Reaktivitäten:
Bovine, Human, Mouse
Buffer:
0.05% sodium azide|PBS, 0.1% rBSA, 0.05% azide
Immunogen:
Purified human IgG (LcN-2 and ICO-106)
Formulierung:
PBS, 0.1% rBSA, 0.05% azide
Klon:
LcN-2 ICO-106
Uniprot:
P01701, P01842
Synonyme:
Ig lambda chain C region MGC;Ig lambda chain V-I region BL2;Ig lambda chain V-I region EPS;Ig lambda chain V-I region NEW;Ig lambda chain V-I region NIG-64;Ig lambda-1 chain C region;ig lambda-6 chain C region;IGL@;IGLC6;IGLV;immunoglobulin lambda gene cluster;immunoglobulin lambda variable group;immunoglobulin lambda variable region gene cluster;Variable region of lambda light chains
Weitere Details:
This MAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Versandbedingungen:
Ambient