BNC740333
CD8(RIV11), CF740 conjugate, 0.1mg/mL
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- BNC740333
- Zusätzliche Namen:
- CD8 antigen, alpha polypeptide (p32), T8/Leu-2 T-lymphocyte differentiation antigen, Ly3, LYT3, MAL, T-cell surface glycoprotein CD8 alpha chain
- Anwendung:
- Flow Cytometry, IF
- Konzentration:
- 0.1 mg/ml
- Molekulargewicht:
- 32 kDa
- Quelle:
- Animal
- Lagerbedingungen:
- 2-8[o]C, RT
- Hersteller:
- Biotium
- Host:
- Mouse
- Reaktivitäten:
- Bovine, Human, Mouse
- Buffer:
- 0.05% sodium azide|PBS, 0.1% rBSA, 0.05% azide
- Immunogen:
- Human peripheral lymphocytes
- Formulierung:
- PBS, 0.1% rBSA, 0.05% azide
- Klon:
- RIV11
- Uniprot:
- P01732
- Synonyme:
- CD8;CD8 antigen, alpha polypeptide (p32);Cgn2;CNCalpha4, CNG5;CNG channel alpha-4;CNG-4;CNG4;cyclic nucleotide gated cation channel;cyclic nucleotide gated channel alpha 4;cyclic nucleotide-gated cation channel alpha-4;cyclic nucleotide-gated olfactory channel subunit OCNC2;Leu2;Leu2 T-lymphocyte antigen;OKT8 T-cell antigen;olfactory cyclic nucleotide-gated channel;p32;rOCNC2;T cell co-receptor;T-cell antigen Leu2;T-cell surface glycoprotein CD8 alpha chain;T-lymphocyte differentiation antigen T8/Leu-2;T8 T-cell antigen
- Weitere Details:
- Recognizes a protein of 32 kDa, identified as CD8a (also known as CD8 chain, T cell co-receptor, Leu2, and T8). CD8 molecule consists of two chains, termed and chain, which are expressed as a disulphide-linked heterodimer or as an homodimer. CD8 is expressed on T cell subset (cytotoxic/suppressor T cells), thymocytes and NK cells. The majority of CD8 T-cells expresses CD8 as heterodimer. Some subpopulation of CD8 T cells as well as NK cells may express homodimer. CD8 functions as a co-receptor in concert with TCR for binding the MHC class I/peptide complex. The HIV-2 envelope glycoprotein binds CD8 chain (but not chain). The cytoplasmic domain of CD8 associates with p56lck tyrosine kinase. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Versandbedingungen:
- Ambient