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  2. Monoclonal

BNC740029

Fibronectin(TV-1), CF740 conjugate, 0.1mg/mL

Eine Lieferung in diese Region ist nicht möglich.

SKU:
BNC740029
Zusätzliche Namen:
Cold insoluble globulin (CIG); FINC; FN1; FNZ; GFND; GFND2; LETS; Migration stimulating factor (MSF); Ugl-Y3
Anwendung:
Flow Cytometry, WB, IHC-P, IHC-Fr
Konzentration:
0.1 mg/ml
Molekulargewicht:
220 kDa (monomer); 440 kDa (dimer)
Quelle:
Animal
Lagerbedingungen:
2-8[o]C, RT
Hersteller:
Biotium
Host:
Mouse
Reaktivitäten:
Bovine, Human, Mouse, Porcine, Rat
Buffer:
0.05% sodium azide|PBS, 0.1% rBSA, 0.05% azide
Immunogen:
T-cell lymphoma biopsy
Formulierung:
PBS, 0.1% rBSA, 0.05% azide
Klon:
TV-1
Uniprot:
P02751
Synonyme:
CIG;cold-insoluble globulin;ED-B;epididymis secretory sperm binding protein;fibronectin;FINC;FN;FNZ;GFND;GFND2;LETS;migration-stimulating factor;MSF;SMDCF
Weitere Details:
Fibronectin is a soluble dimeric glycoprotein of 440 kDa, which is present in cells, extracellular matrix, and blood. This MAb reacts with the cellular as well as plasma form of fibronectin. Reportedly, after iv administration, this MAb localizes to tumor vessels where it binds to the underlying basement. The epitope recognized by this antibody is not accessible to the circulating MAb in normal tissues, indicating that it can be used to specifically target tumor vessels in vivo. TV-1 is reportedly useful for delivering vasoactive agents to tumors to induce increased vascular permeability or blood flow prior to treatment with chemotherapeutic drugs or MAbs.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Versandbedingungen:
Ambient